Global metabolomic analysis for finding biomarker candidates from acute myocardial infarction disease
- Global metabolomic analysis for finding biomarker candidates from acute myocardial infarction disease
- 최종민; 이화정; 정병화
- Myocardial infarction; Metabolomics; Biomarker
- Issue Date
- 2012 추계 대한약학회
- We found separated clustering in multivariate analysis (OPLS-DA) between AMI group and control group, and database search was done to find out proper metabolites to distinguish acute
MI disease. As a result, several lipids and amino acid were identified as biomarker candidates. Several biomarkers such as LysoPC(18:2), LysoPC(18:1), MG(18:0(9Z)/0:0/0:0) were shown
similar intensity change in each CVD disease groups, and this finding might help to find sensitive CVD diagnostic marker.
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- KIST Publication > Conference Paper
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