Detection of the primary lesion in patients with cervical metastases from unknown primary tumors with narrow band imaging endoscopy: Preliminary report

Title
Detection of the primary lesion in patients with cervical metastases from unknown primary tumors with narrow band imaging endoscopy: Preliminary report
Authors
류인선최승호김도훈한명월노종렬김상윤남순열
Keywords
unknown primary neoplasm; narrow-band imaging; endoscopy; head and neck cancer; upper aerodigestive tract
Issue Date
2013-01
Publisher
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
Citation
VOL 35, NO 1, 10-14
Abstract
Background: We investigated whether the addition of narrow band imaging (NBI) to standard diagnostic workups could enhance the detection of primary lesions in patients with carcinoma of unknown primary (CUP). Methods: Thirty patients with CUP underwent NBI endoscopy and fluorodeoxyglucose–positron emission tomography/ CT (FDG-PET/CT) after thorough conventional diagnostic workups between 2009 and 2011. Sites suspected of harboring primary tumors, as determined by NBI and/or FDG-PET/CT, were biopsied for histologic confirmation. Results: Occult primary tumors were identified in 33.3% (10/ 30), including 13.3% (4/30) by NBI and 20.0% (6/30) by FDG-PET/ CT. All of diagnosed lesions by NBI were confirmed histologically as squamous cell carcinomas with T1 classification and identified at 2 supraglottis, 1 hypopharynx, and 1 esophagus, respectively. Conclusions: NBI endoscopy may be a useful method for detecting primary tumors, especially for small and superficial squamous cell carcinomas of the upper aerodigestive tract, after conventional workup in patients with CUP.
URI
http://pubs.kist.re.kr/handle/201004/43857
ISSN
10433074
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KIST Publication > Article
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