Detection of the primary lesion in patients with cervical metastases from unknown primary tumors with narrow band imaging endoscopy: Preliminary report
- Detection of the primary lesion in patients with cervical metastases from unknown primary tumors with narrow band imaging endoscopy: Preliminary report
- 류인선; 최승호; 김도훈; 한명월; 노종렬; 김상윤; 남순열
- unknown primary neoplasm; narrow-band imaging; endoscopy; head and neck cancer; upper aerodigestive tract
- Issue Date
- HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
- VOL 35, NO 1, 10-14
- Background: We investigated whether the addition
of narrow band imaging (NBI) to standard diagnostic
workups could enhance the detection of primary lesions in
patients with carcinoma of unknown primary (CUP).
Methods: Thirty patients with CUP underwent NBI endoscopy
and fluorodeoxyglucose–positron emission tomography/
CT (FDG-PET/CT) after thorough conventional diagnostic workups
between 2009 and 2011. Sites suspected of harboring primary
tumors, as determined by NBI and/or FDG-PET/CT, were
biopsied for histologic confirmation.
Results: Occult primary tumors were identified in 33.3% (10/
30), including 13.3% (4/30) by NBI and 20.0% (6/30) by FDG-PET/
CT. All of diagnosed lesions by NBI were confirmed histologically as
squamous cell carcinomas with T1 classification and identified at 2
supraglottis, 1 hypopharynx, and 1 esophagus, respectively.
Conclusions: NBI endoscopy may be a useful method for
detecting primary tumors, especially for small and superficial
squamous cell carcinomas of the upper aerodigestive tract,
after conventional workup in patients with CUP.
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