Inorganic/Organic Composite Biosensors as a Platform for the Supersensitive Detection and Quantification of Pancreatic Cell Biomarkers

Title
Inorganic/Organic Composite Biosensors as a Platform for the Supersensitive Detection and Quantification of Pancreatic Cell Biomarkers
Authors
황민태이종욱최종훈이관희
Keywords
Pancreatic Cancer; Quantum Dot; Ferritin; Biosensor
Issue Date
2012-10
Publisher
Biomedical Engineering Society (BMES)
Abstract
Recent advances spanning numerous fields of research – biological, chemical, and environmental to name a few – have revealed various nano-sized substances of interest. While sensors, in the broadest sense of the term, are commonly employed to detect such targets, many are inadequate in their ability to both accurately detect and quantify target analyte. For instance, at low analyte concentrations, fluorescent probes are often beset by issues of sensitivity, while nano-sized materials such as liposomes, dendrimers, and gold nanoparticles are affected in their quantitative capacity. In essence, the dichotomy between current technological limitations and the emerging demand for highly sensitive sensors with quantitative capabilities underscore the need for a sensor that allows for both supersensitive detection as well as quantitative analysis. In this study, we propose to construct an inorganic/organic composite biosensor to serve as a platform for the supersensitive detection and quantification of target analytes.
URI
http://pubs.kist.re.kr/handle/201004/43871
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KIST Publication > Conference Paper
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