Inorganic/Organic Composite Biosensors as a Platform for the Supersensitive Detection and Quantification of Pancreatic Cell Biomarkers
- Inorganic/Organic Composite Biosensors as a Platform for the Supersensitive Detection and Quantification of Pancreatic Cell Biomarkers
- 황민태; 이종욱; 최종훈; 이관희
- Pancreatic Cancer; Quantum Dot; Ferritin; Biosensor
- Issue Date
- Biomedical Engineering Society (BMES)
- Recent advances spanning numerous fields of research – biological, chemical, and environmental to name a few – have revealed various nano-sized substances of interest. While sensors, in the broadest sense of the term, are commonly employed to detect such targets, many are inadequate in their ability to both accurately detect and quantify target analyte. For instance, at low analyte concentrations, fluorescent probes are often beset by issues of sensitivity, while nano-sized materials such as liposomes, dendrimers, and gold nanoparticles are affected in their quantitative capacity. In essence, the dichotomy between current technological limitations and the emerging demand for highly sensitive sensors with quantitative capabilities underscore the need for a sensor that allows for both supersensitive detection as well as quantitative analysis. In this study, we propose to construct an inorganic/organic composite biosensor to serve as a platform for the supersensitive detection and quantification of target analytes.
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