Flexible neural probe embedded polymer optical wave guide for optical stimulation

Title
Flexible neural probe embedded polymer optical wave guide for optical stimulation
Authors
이부용박형달박정호김진석
Keywords
MEMS; Neuron; Optical waveguide; Polymer; 초미세전자기계시스템; 신경세포; 광도파로; 고분자
Issue Date
2012-04
Publisher
제14회 한국 MEMS 학술대회
Abstract
Various MEMS based silicon neural probes have been introduced to simultaneously record as well as stimulate multiple sites for studying brain for electrical stimulation. However, electrical stimulation may damage the neurons and also suffers from poor spatial resolution limited by propagation of electrical pulse through neurons and solution. Also, the rigidity of silicon devices induces tissue damage during insertion. So, recently optical stimulation has been reported as an alternative to electrical stimulation with potential advantages such as noncontact stimulation and investigated to selectively stimulate the specific nerves. In this paper, we report a neural probe which can optical stimulate though optical waveguide and record extracellular neural signals though platinum tetrodes. Especially, we use biocompatible and flexible polymer(SU-8) only for probe shank and optical waveguide which can reduce neuron damage during probe insertion compared with Si-based neural probe. And SU-8 waveguide can optical stimulation is enough to optically stimulate neurons.
URI
http://pubs.kist.re.kr/handle/201004/44088
Appears in Collections:
KIST Publication > Conference Paper
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