Load-bearing capacity and biological allowable limit of biodegradable metal based on degradation rate in vivo

Title
Load-bearing capacity and biological allowable limit of biodegradable metal based on degradation rate in vivo
Authors
조성윤채수원최귀원석현광한형섭양석조김영율김종택정재영Michel Assad
Keywords
load bearing; biodegradable alloy; magnesium; degradation rate; implant
Issue Date
2012-08
Publisher
Journal of biomedical materials research. Part B, Applied biomaterials
Citation
VOL 100B, NO 6, 1535-1544
Abstract
In this study, a newly developed Mg-Ca-Zn alloy for low degradation rate and surface erosion properties was evaluated. The compressive, tensile, and fatigue strength were measured before implantation. The degradation behavior was evaluated by analyzing the microstructure and local hardness of the explanted specimen. Mean and maximum degradation rates were measured using micro CT equipment from 4-, 8-, and 16- week explants, and the alloy was shown to display surface erosion properties. Based on these characteristics, the average and minimum load bearing capacities in tension, compression, and bending modes were calculated. According to the degradation rate and references of recommended dietary intakes (RDI), the Mg-Ca-Zn alloy appears to be safe for human use.
URI
http://pubs.kist.re.kr/handle/201004/44105
ISSN
15524973
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KIST Publication > Article
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