In vivo corrosion mechanism by elemental interdiffusion of biodegradable Mg-Ca alloy

Title
In vivo corrosion mechanism by elemental interdiffusion of biodegradable Mg-Ca alloy
Authors
정재영권상준한형섭이지영안재평양석조조성윤차필령김유찬석현광
Keywords
magnesium alloy; corrosion mechanism; in vivo implantation; transmission electron microscopy; interdiffusion
Issue Date
2012-11
Publisher
Journal of biomedical materials research. Part B, Applied biomaterials
Citation
VOL 100B, NO 8, 2251-2260
Abstract
We elucidated the in vivo corrosion mechanism of the biodegradable alloy Mg–10 wt % Ca in rat femoral condyle through transmission electron microscope observations assisted by focused ion beam technique. The alloy consists of a primary Mg phase and a three-dimensional lamellar network of Mg and Mg2Ca. We found that the Mg2Ca is rapidly corroded by interdiffusion of Ca and O, leading to a structural change from lamellar network to nanocrystalline MgO. In contrast to the fast corrosion rate of the lamellar structure, the primary Mg phase slowly changes into nanocrystalline MgO through surface corrosion by O supplied along the lamellar networks. The rapid interdiffusion induces an inhomogeneous Ca distribution and interestingly leads to the formation of a transient CaO phase, which acts as a selective leaching path for Ca. In addition, the outgoing Ca with P from body fluids forms needle-type calcium phosphates similar to hydroxyl apatite at interior and surface of the implant, providing an active biological environment for bone mineralization.
URI
http://pubs.kist.re.kr/handle/201004/44107
ISSN
15524973
Appears in Collections:
KIST Publication > Article
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE