Functional mouse brain mapping and its application to sleep study

Title
Functional mouse brain mapping and its application to sleep study
Authors
최지현E. HWANGB. KIMS. LEES. HANY. KIMR. STRECKER
Keywords
EEG; SLEEP; THALAMOCORTICAL
Issue Date
2012-10
Publisher
Society for neuroscience
Abstract
In 2010, a new methodology called high resolution electroencephalography (HR-EEG) for mouse brain was introduced in Journal of Neurophysiology (Choi JH, Koch KP, Poppendieck W, Lee M, Shin HS (2010) High resolution electroencephalography in freely moving mice. J Neurophysiol 104: 1825-1834; Lee M, Kim D, Shin H-S, Sung H-G, Choi JH (2011) High-density EEG Recordings of the Freely Moving Mice using Polyimidebased Microelectrode. J Vis Exp: e2562). By combining this new technique with conventional local field potential recording in thalamus, we revisited the sleep wave including sleep spindle, K-complex, and slowwave sleep oscillation in the viewpoint of the generation, propagation, and termination of these waves. We analyze the spatio-temporal patterns of the sleep waves and performed causality study between sleep waves in cortex and thalamus. We also analyzed the structures of sleep wave under the condition of acute sleep deprivation as well as chronic sleep deprivation.
URI
http://pubs.kist.re.kr/handle/201004/44189
Appears in Collections:
KIST Publication > Conference Paper
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