Chalcones from the Flowers of Coreopsis lanceolata and Their In Vitro Antioxidative Activity
- Chalcones from the Flowers of Coreopsis lanceolata and Their In Vitro Antioxidative Activity
- 상아방; 사랑게렐; 전제승; 노주원; 엄병헌
- antioxidants; antioxidative activity; chalcones; Coreopsis lanceolata; composites; Compositae; phenolics
- Issue Date
- Planta medica
- VOL 79, NO 3/4, 295-300
- Three new chalcones, 3,2′-dihydroxy-4,3′-dimethoxychalcone-
4′-glucoside (1), 4′-O-(2′′′-O-caffeoyl)
2′,3′,3,4-tetrahydroxychalcone (2), and
along with five known phenolics, were isolated
from Coreopsis lanceolata flowers. The structures
of the new compounds were elucidated by extensive
spectroscopic methods including NMR and
MS. The three new chalcones showed a good in vitro
HepG2 cell protecting effect against tert-butylhydroperoxide-
induced oxidative stress.
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