Chalcones from the Flowers of Coreopsis lanceolata and Their In Vitro Antioxidative Activity

Title
Chalcones from the Flowers of Coreopsis lanceolata and Their In Vitro Antioxidative Activity
Authors
상아방사랑게렐전제승노주원엄병헌
Keywords
antioxidants; antioxidative activity; chalcones; Coreopsis lanceolata; composites; Compositae; phenolics
Issue Date
2013-03
Publisher
Planta medica
Citation
VOL 79, NO 3/4, 295-300
Abstract
Three new chalcones, 3,2′-dihydroxy-4,3′-dimethoxychalcone- 4′-glucoside (1), 4′-O-(2′′′-O-caffeoyl) 2′,3′,3,4-tetrahydroxychalcone (2), and 2′,4′,3-trihydroxy-3′,4-dimethoxychalcone (3), along with five known phenolics, were isolated from Coreopsis lanceolata flowers. The structures of the new compounds were elucidated by extensive spectroscopic methods including NMR and MS. The three new chalcones showed a good in vitro HepG2 cell protecting effect against tert-butylhydroperoxide- induced oxidative stress.
URI
http://pubs.kist.re.kr/handle/201004/44618
ISSN
00320943
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KIST Publication > Article
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