Target-specific photocatalyst for selective killing of bacteria

Title
Target-specific photocatalyst for selective killing of bacteria
Authors
송민영정현덕정종수김병찬
Keywords
TiO2; Antibody; Selective killing; E.coli
Issue Date
2013-06
Publisher
2013 Internatinoal Environmental Engineering Conference
Abstract
Infection from microorganisms can result in serious problems such as food poisoning, enteritis, and SARS. To prevent infection from microorganisms numerous antimicrobial methods such as filtration, thermal treatment, antibiotic agent treatment, disinfectant treatment, and ultraviolet (UV) irradiation were studied, and evaluated for their effectiveness against different microorganisms and environmental conditions. Interestingly, however, these studies have been dedicated to the non-selective inactivation of microorganisms. Most methods of microorganism sterilization are non-specific, and useful microorganisms are killed alongside target microorganisms. In the present work, we prepared bacterial target-specific TiO2 particles for enhancement of antibacterial effects and the target specific killing of bacteria in aqueous environments. To develop a target-specific antibacterial method we prepared TiO2 particles conjugated with bacteria-specific antibody (E. coli polyclonal antibody, AbE) and evaluated their selective antibacterial performance in targeting Escherichia coli (E. coli) as a model.
URI
http://pubs.kist.re.kr/handle/201004/45010
Appears in Collections:
KIST Publication > Conference Paper
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