Target-specific photocatalyst for selective killing of bacteria
- Target-specific photocatalyst for selective killing of bacteria
- 송민영; 정현덕; 정종수; 김병찬
- TiO2; Antibody; Selective killing; E.coli
- Issue Date
- 2013 Internatinoal Environmental Engineering Conference
- Infection from microorganisms can result in serious problems such as food poisoning, enteritis, and SARS. To prevent infection from microorganisms numerous antimicrobial methods such as filtration, thermal treatment, antibiotic agent treatment, disinfectant treatment, and ultraviolet (UV) irradiation were studied, and evaluated for their effectiveness against different microorganisms and environmental conditions. Interestingly, however, these studies have been dedicated to the non-selective inactivation of microorganisms. Most methods of microorganism sterilization are non-specific, and useful microorganisms are killed alongside target microorganisms.
In the present work, we prepared bacterial target-specific TiO2 particles for enhancement of antibacterial effects and the target specific killing of bacteria in aqueous environments. To develop a target-specific antibacterial method we prepared TiO2 particles conjugated with bacteria-specific antibody (E. coli polyclonal antibody, AbE) and evaluated their selective antibacterial performance in targeting Escherichia coli (E. coli) as a model.
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