Biodegradability engineering of biodegradable Mg alloys: Tailoring the electrochemical properties and microstructure of constituent phases
- Biodegradability engineering of biodegradable Mg alloys: Tailoring the electrochemical properties and microstructure of constituent phases
- 차필령; 한형섭; 양귀복; 김유찬; 홍기하; 이승철; 정재영; 안재평; 김영율; 조성윤; 변지영; 이강식; 양석조; 석현광
- Biodegradable metal; Magnesium alloy; electrochemical properety; microstructural engineering
- Issue Date
- Scientific Reports
- VOL 3, 2367-1-2367-6
- Crystalline Mg-based alloys with a distinct reduction in hydrogen evolution were prepared through both
electrochemical and microstructural engineering of the constituent phases. The addition of Zn to Mg-Ca
alloy modified the corrosion potentials of two constituent phases (Mg 1 Mg2Ca), which prevented the
formation of a galvanic circuit and achieved a comparable corrosion rate to high purity Mg. Furthermore,
effective grain refinement induced by the extrusion allowed the achievement of much lower corrosion rate
than high purity Mg. Animal studies confirmed the large reduction in hydrogen evolution and revealed good
tissue compatibility with increased bone deposition around the newly developed Mg alloy implants. Thus,
high strength Mg-Ca-Zn alloys with medically acceptable corrosion rate were developed and showed great
potential for use in a new generation of biodegradable implants.
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