Simultaneous quantitative analysis of tryptophan and its metabolites in plasma using LC-MS/MS

Title
Simultaneous quantitative analysis of tryptophan and its metabolites in plasma using LC-MS/MS
Authors
최종민이화정정병화
Issue Date
2013-08
Publisher
한국질량분석학회 여름정기학술대회
Abstract
Tryptophan is an essential amino acid. This amino acid and its metabolites are mostly biologically active and related to pathogenesis of various diseases. Therefore it is noteworthy to quantify tryptophan and its metabolites to identify their functions. In this study the quantitative analytical method for tryptophan and its 6 metabolites (indole-3-lactic acid, anthranilic acid, nicotinic acid, kynurenine, kynurenic acid and 3-indoxyl sulfate) in plasma was developed using liquid chromatography-tandem mass spectrometry (LC-MS/MS).
URI
http://pubs.kist.re.kr/handle/201004/45765
Appears in Collections:
KIST Publication > Conference Paper
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