Magnetic nanoparticles size influences uptake in primary Schwann cells
- Magnetic nanoparticles size influences uptake in primary Schwann cells
- 김동휘; 추준욱; 최귀원; 박종웅; 윤인찬
- Magnetic nanoparticles; primary Schwann cell culture; cell uptake; nerve regeneration
- Issue Date
- Asian Pacific
Conference on Biomechanics
- Schwann cells are the glial cells of peripheral nervous system (PNS) which myelinate for axons. Schwann cells functions are important for proper development, homeostasis, and regeneration of the PNS. Previous studies presented Schwann cells can be isolated and expanded in culture. For biomedical applications, the effect of magnetic nanoparticles (MNPs) has increased significantly past decade. MNPs are used to apply many diagnostic tools for contrast agents in MR (magnetic resonance) imaging or magnetic vectors for drug delivery. MNPs has potentials which controlling the direction or movement of MNPs and ability to deliver chemicals or biomolecules by an external magnetic field. It proposes that MNPs could be promoted to enhance or accelerate nerve regeneration and to provide guidance for regenerating axons. In this study, we present a study on uptake in primary Schwann cells using diversified MNPs size.
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