Magnetic nanoparticles size influences uptake in primary Schwann cells

Title
Magnetic nanoparticles size influences uptake in primary Schwann cells
Authors
김동휘추준욱최귀원박종웅윤인찬
Keywords
Magnetic nanoparticles; primary Schwann cell culture; cell uptake; nerve regeneration
Issue Date
2013-08
Publisher
Asian Pacific Conference on Biomechanics
Abstract
Schwann cells are the glial cells of peripheral nervous system (PNS) which myelinate for axons. Schwann cells functions are important for proper development, homeostasis, and regeneration of the PNS. Previous studies presented Schwann cells can be isolated and expanded in culture. For biomedical applications, the effect of magnetic nanoparticles (MNPs) has increased significantly past decade. MNPs are used to apply many diagnostic tools for contrast agents in MR (magnetic resonance) imaging or magnetic vectors for drug delivery. MNPs has potentials which controlling the direction or movement of MNPs and ability to deliver chemicals or biomolecules by an external magnetic field. It proposes that MNPs could be promoted to enhance or accelerate nerve regeneration and to provide guidance for regenerating axons. In this study, we present a study on uptake in primary Schwann cells using diversified MNPs size.
URI
http://pubs.kist.re.kr/handle/201004/45922
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KIST Publication > Conference Paper
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