CoryneBrick vectors: A synthetic biology platform for gene expression in Corynebacterium glutamicum

Title
CoryneBrick vectors: A synthetic biology platform for gene expression in Corynebacterium glutamicum
Authors
강민경이정석엄영순우한민
Issue Date
2013-10
Publisher
2013년도 한국생물공학회 춘계학술발표대회 및 국제심포지엄
Abstract
The standardized synthetic platforms for the production of industrial interests have been developed and implemented in microbial cells. However, most synthetic tools have been designed and constructed for model organisms such as Escherichia coli and Saccharomyces cerevisiae. Corynebacterium glutamicum is well-known industrial microorganism in amino acid production. In this study, we established a synthetic biological platform, CoryneBrick, which a collection of E.coli-C. glutamicum shuttle vectors with different inducible promoters, and antibiotic resistance markers in a framework of BioBrick standard parts for controllable gene expressions in C. glutamicum. This platform could be used as a useful engineering tool for Corynebacteria industry. This work was supported by the National Research Foundation of Korea Grant funded by the Korean Government (MEST) (2013, University-Institute cooperation program) and ‘Creative Allied Program (CAP)’ through the Korea Research Council of Fundamental Science and Technology (KRCF) and Korea Institute of Science and Technology (KIST).
URI
http://pubs.kist.re.kr/handle/201004/46040
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KIST Publication > Conference Paper
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