Mapping mammalian synaptic connectivity

Title
Mapping mammalian synaptic connectivity
Authors
육채현Shaul Druckmann김진현
Keywords
Synaptic connectivity; Brainbow; Array tomography; mGRASP; Trans-synaptic tracer; Neurological disorders
Issue Date
2013-12
Publisher
Cellular and molecular life sciences : CMLS
Citation
VOL 70, NO 24, 4747-4757
Abstract
Mapping mammalian synaptic connectivity has long been an important goal of neuroscientists since it is considered crucial for explaining human perception and behavior. Yet, despite enormous efforts, the overwhelming complexity of the neural circuitry and the lack of appropriate techniques to unravel it have limited the success of efforts to map connectivity. However, recent technological advances designed to overcome the limitations of conventional methods for connectivity mapping may bring about a turning point. Here, we address the promises and pitfalls of these new mapping technologies.
URI
http://pubs.kist.re.kr/handle/201004/46233
ISSN
1420682X
Appears in Collections:
KIST Publication > Article
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