Clinical outcomes of patients with salivary gland carcinomas preoperatively misdiagnosed as benign lesions

Title
Clinical outcomes of patients with salivary gland carcinomas preoperatively misdiagnosed as benign lesions
Authors
In Sun RyuJong-Lyel RohKyung-Ja ChoSang-wook LeeSeung-Ho ChoiSoon Yuhl Nam김상윤
Keywords
salivary gland carcinomas; preoperative cytology; outcomes; diagnosis; recurrence
Issue Date
2013-12
Publisher
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
Citation
VOL 35, NO 12, 1764-1770
Abstract
Background We compared clinical outcomes between patients with salivary gland carcinomas preoperatively misdiagnosed as benign lesion and properly diagnosed as malignant lesion. Methods The outcomes were compared between patients with benign lesion and malignant lesion (44 each) on preoperative fine-needle aspiration cytology diagnosis who underwent conservative or radical surgery. Results Five-year lesion-free survival (DFS) rates were 86.8% for benign lesion and 76.3% for malignant lesion (p = .128). Surgical extent did not significantly affect locoregional recurrence and DFS (p = .360). Univariate analysis showed that sublingual gland tumor, positive resection margin, and extraparenchymal extension (EPE) were significantly associated with DFS (p < .05 each). On multivariate analysis, EPE remained an independent variable (p = .047, hazard ratio = 6.621, 95% confidence interval = 1.393&#8211;31.474). Conclusions The clinical outcomes of patients with salivary gland carcinomas misdiagnosed as benign are relatively favorable. Conservative surgery may be sufficient for patients with low-grade and T1&#8211;2 salivary gland carcinomas
URI
http://pubs.kist.re.kr/handle/201004/46277
ISSN
10433074
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KIST Publication > Article
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