Diagnostic accuracy of computed tomography findings for patients undergoing salvage total laryngectomy

Title
Diagnostic accuracy of computed tomography findings for patients undergoing salvage total laryngectomy
Authors
MYUNG WOUL HANSUN-A KIMKYUNG-JA CHOJEONG HYUN LEEHYUN KYUNG LIMJONG-LYEL ROHSEUNG-HO CHOI김상윤SOON YUHL NAM
Keywords
Larynx cancer; radiotherapy; salvage surgery; computed tomography; CT
Issue Date
2013-06
Publisher
Acta oto-laryngologica
Citation
VOL 133, 620-625
Abstract
Conclusions: Computed tomography (CT) imaging has clear limitations for the diagnosis of cartilage invasion or tumor spread in recurrent laryngeal cancer. Alternative methods of pretreatment assessment are needed for recurrent laryngeal cancer. Objectives: The diagnosis and staging of recurrent laryngeal cancer, previously treated by radiation therapy (RT), remains challenging. Practically, surgeons need to depend on imaging to predict which patients will have a chance for conservation salvage laryngectomy. The purpose of the present study was to determine the accuracy of preoperative CT performed for recurrent laryngeal carcinoma evaluation following RT. Methods: This retrospective review identified 32 patients who underwent salvage total laryngectomy after RT from 1998 to 2010. For our radiologic classification of the thyroid cartilage, we analyzed the conditions as normal, sclerosis, invasion, penetration, and extralaryngeal spread and categorized the state of the arytenoids and cricoid into three possible conditions: normal, sclerosis, and destruction. Radiographic findings were correlated with pathology findings. Results: Sensitivity and specificity for the detection of the thyroid cartilage infiltration were 57% and 94%, 50% and 89% for the cricoid cartilage, and 33% and 76% for arytenoid cartilage, respectively. The accuracy of recurrent tumor classification was 59.4%. Three carcinomas were over-staged and 10 were under-staged.
URI
http://pubs.kist.re.kr/handle/201004/46279
ISSN
00016489
Appears in Collections:
KIST Publication > Article
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