Diagnostic accuracy of computed tomography findings for patients undergoing salvage total laryngectomy
- Diagnostic accuracy of computed tomography findings for patients undergoing salvage total laryngectomy
- MYUNG WOUL HAN; SUN-A KIM; KYUNG-JA CHO; JEONG HYUN LEE; HYUN KYUNG LIM; JONG-LYEL ROH; SEUNG-HO CHOI; 김상윤; SOON YUHL NAM
- Larynx cancer; radiotherapy; salvage surgery; computed tomography; CT
- Issue Date
- Acta oto-laryngologica
- VOL 133, 620-625
- Conclusions: Computed tomography (CT) imaging has clear limitations for the diagnosis of cartilage invasion or tumor spread
in recurrent laryngeal cancer. Alternative methods of pretreatment assessment are needed for recurrent laryngeal cancer.
Objectives: The diagnosis and staging of recurrent laryngeal cancer, previously treated by radiation therapy (RT), remains
challenging. Practically, surgeons need to depend on imaging to predict which patients will have a chance for conservation
salvage laryngectomy. The purpose of the present study was to determine the accuracy of preoperative CT performed for
recurrent laryngeal carcinoma evaluation following RT. Methods: This retrospective review identified 32 patients who
underwent salvage total laryngectomy after RT from 1998 to 2010. For our radiologic classification of the thyroid cartilage,
we analyzed the conditions as normal, sclerosis, invasion, penetration, and extralaryngeal spread and categorized the state of
the arytenoids and cricoid into three possible conditions: normal, sclerosis, and destruction. Radiographic findings were
correlated with pathology findings. Results: Sensitivity and specificity for the detection of the thyroid cartilage infiltration were
57% and 94%, 50% and 89% for the cricoid cartilage, and 33% and 76% for arytenoid cartilage, respectively. The accuracy of
recurrent tumor classification was 59.4%. Three carcinomas were over-staged and 10 were under-staged.
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