Protective effects of chlorogenic acid metabolites and coffee extract on oxidative and endoplasmic reticulumstress-induced retinal degeneration

Title
Protective effects of chlorogenic acid metabolites and coffee extract on oxidative and endoplasmic reticulumstress-induced retinal degeneration
Authors
장호림김경아조형안홍열이은하정상훈이창용
Issue Date
2013-08
Publisher
한국식품과학회지
Abstract
Coffee is one of the most popular and consumed beverages in the world and is associated with a series of benefits for human health. Chlorogenic acids, the most abundant secondary metabolites in coffee during the coffee brewing process, have several pharmacological activities including antioxidant, hepato-protectant, antibacterial, antihistaminic, and anticancer, among others. However, there is lack of studies for neuroprotective effect of chlorogenic acids and its metabolites especially in the retina. Chlorogenic acids and coffee extracts reduce retinal degeneration from oxidative and ER stress in vitro and in vivo. Also, metabolites of chlorogenic acids, 3,4-dihydroxyphenylacetic acid and 3-(4-hydroxyphenyl) propionic acid, might be a potential therapeutic agent for retinal degeneration.
URI
http://pubs.kist.re.kr/handle/201004/46671
ISSN
03676293
Appears in Collections:
KIST Publication > Conference Paper
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE