Immunomagnetic nanoparticle-based assays for detection of biomarkers

Title
Immunomagnetic nanoparticle-based assays for detection of biomarkers
Authors
박호영황민태이관희
Keywords
magnetic; multiplex; signal control; microfluidics; microarrays; automation
Issue Date
2013-11
Publisher
International journal of nanomedicine
Citation
VOL 8, 4543-4552
Abstract
The emergence of biomarkers as key players in the paradigm shift towards preventative medicine underscores the need for their detection and quantification. Advances made in the field of nanotechnology have played a crucial role in achieving these needs, and have contributed to recent advances in the field of medicine. Nanoparticle-based immunomagnetic assays, in particular, offer numerous advantages that utilize the unique physical properties of magnetic nanoparticles. In this review, we focus on recent developments and trends with regards to immunomagnetic assays used for detection of biomarkers. The various immunomagnetic assays are categorized into the following: particle-based multiplexing, signal control, microfluidics, microarray, and automation. Herein, we analyze each category and discuss their advantages and disadvantages.
URI
http://pubs.kist.re.kr/handle/201004/46707
ISSN
11782013
Appears in Collections:
KIST Publication > Article
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