Characterization of core-shell calcium-alginate macrocapsules fabricated by electro-coextrusion

Title
Characterization of core-shell calcium-alginate macrocapsules fabricated by electro-coextrusion
Authors
Natthiya PhawaphuthanonShabnam Behnam구송이판철호Donghwa Chung
Keywords
Electro-coextrusion; Core-shell; Calcium-alginate macrocapsules
Issue Date
2014-04
Publisher
International journal of biological macromolecules
Citation
VOL 65, 267-274
Abstract
Spherical macrocapsules, where calcium-alginate shell enclosed olive oil as a model core medium, were fabricated by electro-coextrusion. The effects of three key process factors, including alginate concentration in shell fluid (0.5–4.0%), shell-to-core flow rate ratio (4–12 at a fixed core flow rate of 0.05 mL/min), and applied voltage (0–10 kV), on the morphological and textural characteristics of the macrocapsules were analyzed using response surface methodology. The analysis showed that the diameter, shell thickness, hardness, and breaking energy of the macrocapsules were in the ranges of 0.89–1.61 mm, 17.4–66.4 μm, 1.37–11.01 N, and 0.34–6.90 mJ, respectively, and strongly influenced by all the three factors, except that the surface appearance was only significantly affected by the shell-to-core flow rate ratio. The process factors were also optimized for the practically useful macrocapsules, having non-oily surface and hardness larger than 3 N, using a graphical optimization technique.
URI
http://pubs.kist.re.kr/handle/201004/47301
ISSN
01418130
Appears in Collections:
KIST Publication > Article
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