Pressure-driven fast reaction and recovery of peptide for an electronic nose application
- Pressure-driven fast reaction and recovery of peptide for an electronic nose application
- 유용경; 이상명; 채명식; 강지윤; 김태송; 황교선; 이정훈
- Microcantilever; Rresonant frequency; peptide
- Issue Date
- Applied physics letters
- VOL 104, NO 8, 083704-1-083704-5
- Combining a highly sensitive sensor platform with highly selective recognition elements is essential for micro/nanotechnology-based electronic nose applications. Particularly, the regeneration sensor surface and its conditions are key issues for practical e-nose applications. We propose a highly sensitive piezoelectric-driven microcantilever array chip with highly selective peptide receptors. By utilizing the peptide receptor, which was discovered by a phase display screening process, we immobilized a dinitrotoluene (DNT) specific peptide as well as a DNT nonspecific peptide on the surface of the cantilever array. The delivery of DNT gas via pressure-driven flow led to a greater instant response of ∼30 Hz, compared to diffusion only (∼15 Hz for 15 h). Using a simple pressure-driven air flow of ∼50 sccm, we confirmed that a ratio of ∼70% of the specific-bounded sites from DNT gas molecules could be regenerated, showing re-usability of the peptide receptor in on-site monitoring for electronic nose applications.
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