Pressure-driven fast reaction and recovery of peptide for an electronic nose application

Title
Pressure-driven fast reaction and recovery of peptide for an electronic nose application
Authors
유용경이상명채명식강지윤김태송황교선이정훈
Keywords
Microcantilever; Rresonant frequency; peptide
Issue Date
2014-02
Publisher
Applied physics letters
Citation
VOL 104, NO 8, 083704-1-083704-5
Abstract
Combining a highly sensitive sensor platform with highly selective recognition elements is essential for micro/nanotechnology-based electronic nose applications. Particularly, the regeneration sensor surface and its conditions are key issues for practical e-nose applications. We propose a highly sensitive piezoelectric-driven microcantilever array chip with highly selective peptide receptors. By utilizing the peptide receptor, which was discovered by a phase display screening process, we immobilized a dinitrotoluene (DNT) specific peptide as well as a DNT nonspecific peptide on the surface of the cantilever array. The delivery of DNT gas via pressure-driven flow led to a greater instant response of ∼30 Hz, compared to diffusion only (∼15 Hz for 15 h). Using a simple pressure-driven air flow of ∼50 sccm, we confirmed that a ratio of ∼70% of the specific-bounded sites from DNT gas molecules could be regenerated, showing re-usability of the peptide receptor in on-site monitoring for electronic nose applications.
URI
http://pubs.kist.re.kr/handle/201004/47319
ISSN
00036951
Appears in Collections:
KIST Publication > Article
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