Discovery of lipid biomarker candidates for myocardial infarction and angina pectoris using lipidomic approach

Title
Discovery of lipid biomarker candidates for myocardial infarction and angina pectoris using lipidomic approach
Authors
최종민이화정정병화
Keywords
Lipidomics; Myocardial infarction; Angina pectoris; Lipid biomarker
Issue Date
2014-04
Publisher
한국대사체학회
Abstract
A simple and rapid lipidomic methodology using UPLC-QTOF-MS to detect and identify lipid metabolites from human serum was used in this study. The human serum samples from healthy control group, stable angina patient group and unstable angina / myocardial infarction patient group were successfully analyzed and significant differences in lipid profiles were found especially in phosphatidylcholines, lysophosphatidylcholines and fatty acids. These findings might be helpful to search the diagnostic biomarker of stable angina and myocardial infarction.
URI
http://pubs.kist.re.kr/handle/201004/47425
Appears in Collections:
KIST Publication > Conference Paper
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