Recent progress in development of synthetic biology platforms and metabolic engineering of Corynebacterium glutamicum

Title
Recent progress in development of synthetic biology platforms and metabolic engineering of Corynebacterium glutamicum
Authors
우한민박진병
Keywords
Corynebacterium glutamicum; synthetic biology; metabolic engineering; industiral host
Issue Date
2014-06
Publisher
Journal of biotechnology
Citation
VOL 180, 43-51
Abstract
The paradigm of synthetic biology has been evolving, along with relevant engineering, to achieve designedbio-systems. Synthetic biology has reached the point where it is possible to develop microbial strainsto produce desired chemicals. Recent advances in this field have promoted metabolic engineering ofCorynebacterium glutamicum as an amino-acid producer for use in intelligent microbial-cell factories.Here, we review recent advances that address C. glutamicum as a potential model organism for syntheticbiology, and evaluate their industrial applications. Finally, we highlight the perspective of developingC. glutamicum as a step toward advanced microbial-cell factories that could produce valuable chemicalsfrom renewable resources.
URI
http://pubs.kist.re.kr/handle/201004/47497
ISSN
01681656
Appears in Collections:
KIST Publication > Article
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