Investigation of Functional Connectivity in Degenerative Retina Using MEA-STA System

Title
Investigation of Functional Connectivity in Degenerative Retina Using MEA-STA System
Authors
문혁준강동훈박재홍형수진신현준서준교
Issue Date
2014-07
Publisher
International Meeting on Substrate-Integrated Microelectrode Arrays
Citation
, 103-104
Abstract
With the trend of population ageing, the number of people experiencing vision loss by retinal degeneration disease, such as age-related macular degeneration(AMD) and retinitis pigmentosa(RP), has increased dramatically. Recently, several electrical/optogenetics retinal prosthesis(implant) schemes that stimulate remaining cells in the retina instead of lost photoreceptors have been proposed. However, degenerated retinas may have distorted neural circuits and functional connectivity among remaining cells is hardly researched, which may be a critical key for the high level vision prosthesis. Therefore, we suggest a method using MEA and spike-triggered average stimulus analysis to investigate the functional connectivity among remaining cells in degenerative retina.
URI
http://pubs.kist.re.kr/handle/201004/47930
ISSN
21991596
Appears in Collections:
KIST Publication > Conference Paper
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