Theranostic nanoparticles for future personalized medicine

Title
Theranostic nanoparticles for future personalized medicine
Authors
류주희이상민손소희김선화James F. Leary최귀원권익찬
Keywords
Theranostics; Personalized medicine; Molecular imaging; Monitoring response
Issue Date
2014-09
Publisher
Journal of controlled release
Citation
VOL 190, 477-484
Abstract
The concept of personalized medicine has recently emerged as a promising way to address unmet medical needs. Due to the limitations of standard diagnostic and therapeutic strategies, the disease treatment is moving towards tailored treatment for individual patients, considering the inter-individual variability in therapeutic response. Theranostics, which involves the combination of therapy and diagnostic imaging into a single system, may fulfill the promise of personalized medicine. By integrating molecular imaging functionalities into therapy, theranostic approach could be advantageous in therapy selection, treatment planning, objective response monitoring and follow-up therapy planning based on the specific molecular characteristics of a disease. Although the field of therapy and imaging of its response have been independently developed thus far, developing imaging strategies can be fully exploited to revolutionize the theranostic systems in combination with the therapy modality. In this review,we describe the recent advances inmolecular imaging technologies that have been specifically developed to evaluate the therapeutic efficacy for theranostic purposes.
URI
http://pubs.kist.re.kr/handle/201004/48701
ISSN
01683659
Appears in Collections:
KIST Publication > Article
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