Preparation of Conjugated Polymer Dots as a Fluorescence Turn-On Assay for Bovine Serum Albumin by Interaction with Graphene Oxide

Title
Preparation of Conjugated Polymer Dots as a Fluorescence Turn-On Assay for Bovine Serum Albumin by Interaction with Graphene Oxide
Authors
Jaeguk NohSangho SonYongkyun KimByung-Jae Chae구본철Taek Seung Lee
Keywords
Sensors; conjugated polymer dot; fluorescence; bovine serum albumin; graphene oxide
Issue Date
2014-11
Publisher
Molecular crystals and liquid crystals
Citation
VOL 600, 170-178
Abstract
Fluorescent conjugated polymers with various monomer compositions were synthesized via Suzuki coupling polymerization and spherically-shaped conjugated polymer dots (CPdot) with uniform size were prepared via conventional reprecipitation technique. Chemically modified graphene oxide (GO) was prepared to use as a component of sensor platform for protein detection. GO showed an excellent interaction with CPdot on its surface via hydrophobic interaction, which, in turn, induced the quenching of the fluorescence of CPdot. Upon exposure to bovine serum albumin (BSA), the quenched fluorescence was recovered, resulting from the release of CPdot from the complex with GO, as BSA adsorbed preferentially on the GO surface.
URI
http://pubs.kist.re.kr/handle/201004/48808
ISSN
15421406
Appears in Collections:
KIST Publication > Article
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