Preparation of Conjugated Polymer Dots as a Fluorescence Turn-On Assay for Bovine Serum Albumin by Interaction with Graphene Oxide
- Preparation of Conjugated Polymer Dots as a Fluorescence Turn-On Assay for Bovine Serum Albumin by Interaction with Graphene Oxide
- Jaeguk Noh; Sangho Son; Yongkyun Kim; Byung-Jae Chae; 구본철; Taek Seung Lee
- Sensors; conjugated
polymer dot; fluorescence; bovine serum albumin; graphene oxide
- Issue Date
- Molecular crystals and liquid crystals
- VOL 600, 170-178
- Fluorescent conjugated polymers with various monomer compositions were synthesized
via Suzuki coupling polymerization and spherically-shaped conjugated polymer dots
(CPdot) with uniform size were prepared via conventional reprecipitation technique.
Chemically modified graphene oxide (GO) was prepared to use as a component of
sensor platform for protein detection. GO showed an excellent interaction with CPdot
on its surface via hydrophobic interaction, which, in turn, induced the quenching of the
fluorescence of CPdot. Upon exposure to bovine serum albumin (BSA), the quenched
fluorescence was recovered, resulting from the release of CPdot from the complex with
GO, as BSA adsorbed preferentially on the GO surface.
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