Proteinticle/Gold Core/Shell Nanoparticles for Targeted Cancer Therapy without Nanotoxicity

Title
Proteinticle/Gold Core/Shell Nanoparticles for Targeted Cancer Therapy without Nanotoxicity
Authors
권구철류주희이종환이은정권익찬김광명이지원
Keywords
proteinticle; gold nanoparticle; core/shell; nanotoxicity; photothermal therapy
Issue Date
2014-10
Publisher
Advanced materials
Citation
VOL 26, NO 37, 6436-6441
Abstract
PGCS-NPs (40 nm) with excellent photo­thermal activity are developed, on the surface of which affibody peptides with specific affinity for EGFR and many small gold dots (1–3 nm) are densely presented. The IV-injected PGCS-NPs into EGFR-expressing tumor-bearing mice successfully perform targeted and photothermal therapy of cancer. It seems that the small gold dots released from disassembled PGCS-NPs are easily removed and never cause in vivo toxicity problems.
URI
http://pubs.kist.re.kr/handle/201004/48896
ISSN
09359648
Appears in Collections:
KIST Publication > Article
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE