Implantable Nerve Cuff Electrode with Conductive Polymer for Improving Recording Signal Quality at Peripheral Nerve

Title
Implantable Nerve Cuff Electrode with Conductive Polymer for Improving Recording Signal Quality at Peripheral Nerve
Authors
박성진이이재윤광석강지윤이수현
Keywords
Journal of Sensor Science and Technology; Neural signal recording; Iridium oxide; PEDOT:pTS; ex-vivo test
Issue Date
2015-01
Publisher
Journal of Sensor Science and Technology
Citation
VOL 24, NO 1, 22-28
Abstract
This study demonstrates a polyimide nerve cuff electrode with a conductive polymer for improving recording signal quality at peripheral nerve. The nerve cuff electrodes with platinum (Pt), iridium oxide (IrOx), and poly(3,4-ethylenedioxythiophene): p-toluene sulfonate (PEDOT:pTS) were fabricated and investigated their electrical characteristics for improving recorded nerve signal quality. The fabricated nerve cuff electrodes with Pt, IrOx, and PEDOT:pTS were characterized their impedance and CDC by using electrochemical impedance spectroscopy (EIS) and cyclic voltammetry. The impedance of PEDOT:pTS measured at 1 kHz was 257Ω, which was extremely lower than the value of the nerve cuff electrodes with IrOx (15897Ω) and Pt (952Ω), respectively. Furthermore, the charge delivery capacity (CDC) of the nerve cuff electrode with PEDOT:pTS was dramatically increased to 62 times than the nerve cuff electrode with IrOx. In ex-vivo test using extracted sciatic nerve of spaque-dawley rat (SD rat), the PEDOT:pTS group exhibited higher signal- to-interference ratio than IrOx group. These results indicated that the nerve cuff electrode with PEDOT:pTS is promising for effective implantable nerve signal recording.
URI
http://pubs.kist.re.kr/handle/201004/50115
ISSN
12255475
Appears in Collections:
KIST Publication > Article
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