Development of Inductive and Capacitive Type Intraocular Pressure (IOP) Sensor to Improve Sensitivity and Minimize Size

Title
Development of Inductive and Capacitive Type Intraocular Pressure (IOP) Sensor to Improve Sensitivity and Minimize Size
Authors
장철인신경식윤광석김용우강지윤이수현
Keywords
Glaucoma; Intraocular pressure (IOP); IOP sensor; in-vivo; wireless; implantable
Issue Date
2014-11
Publisher
Journal of Sensor Science and Technology
Citation
VOL 23, NO 6, 409-415
Abstract
We had presented an inductive type intraocular pressure sensor (L-sensor) in previous work. The distance between a micro coil and a ferrite on the membrane was modulated by pressure, and as a result the inductance and resonant frequency were changed. However, L-sensor has some problems to implant in eyes. First problem is low sensitivity. When L-sensor was implanted in rabbit’s eyes, resonant frequency of L-sensor was very hard to detect. Second problem is biocompatibility. Size of L-sensor is 6×7×1.2mm. When L-sensor was implanted in the eyes, it caused the inflammation. Therefore, this study suggests an inductive and capacitive type IOP sensor (LCsensor). The sensitivity of the LC-sensor 27.3 kHz/mmHg under 60mmHg. It is much larger than 14 kHz/mmHg of the L-sensor. And the size of LC-sensor is 47% smaller than L-sensor. After 2 weeks from the implantation of LC-sensor into rabbit eyes, we measured the changes of resonant frequency of LC-sensor according to increased IOP by Balanced Salt Solution (BSS) injection. As a result, the sensitivity of LC-sensor in in vivo test is 25 kHz/mmHg. That is similar to the sensitivity of in vitro test.
URI
http://pubs.kist.re.kr/handle/201004/50116
ISSN
12255475
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KIST Publication > Article
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