Structured synaptic connectivity between hippocampal regions

Title
Structured synaptic connectivity between hippocampal regions
Authors
Shaul Druckmann린칭이보경육채현Ting ZhaoJeffrey C. Magee김진현
Issue Date
2014-02
Publisher
Neuron
Citation
VOL 81, NO 3, 629-640
Abstract
The organization of synaptic connectivity within a neuronal circuit is a prime determinant of circuit function. We performed a comprehensive fine-scale circuit mapping of hippocampal regions (CA3-CA1) using the newly developed synapse labeling method, mGRASP. This mapping revealed spatially nonuniform and clustered synaptic connectivity patterns. Furthermore, synaptic clustering was enhanced between groups of neurons that shared a similar developmental/migration time window, suggesting a mechanism for establishing the spatial structure of synaptic connectivity. Such connectivity patterns are thought to effectively engage active dendritic processing and storage mechanisms, thereby potentially enhancing neuronal feature selectivity.
URI
http://pubs.kist.re.kr/handle/201004/50217
ISSN
08966273
Appears in Collections:
KIST Publication > Article
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE