Functional Connectivity Change of the Rat Brain in Response to Sensory Stimuli Using Functional Near-Infrared Brain Imagin
- Functional Connectivity Change of the Rat Brain in Response to Sensory Stimuli Using Functional Near-Infrared Brain Imagin
- 김성우; 백승호; 송강일; 양세정; 윤인찬; 김법민; 성준경
- Diffuse optical tomography; Functional
brain connectivity; Hemodynamic response
- Issue Date
- Biomedical Engineering Letters
- VOL 4, 370-377
- Purpose Because the brain can divide into many separateregions structurally and these regions don’t exist independentlyin terms of their function, there are some tendencies betweenthese regions. Methods This functional connectivity has been analyzedusing functional magnetic resonance imaging (fMRI), but inrecent, diffuse optical tomography (DOT) has started toanalyze these connectivity. In our experiment, we measuredthe coactivation in brain regions in response to sensorystimulation using CW-DOT. Results Concentration changes in oxyhemoglobin anddeoxyhemoglobin was calculated using reconstructed absorptioncoefficients at each nodes in finiteelement mesh. Then thesetime-series node data were mapped on our rat brain MRimage. In addition, we analyzed coactivation by calculatingcorrelation coefficients between time-series node data andstandard response pattern of two parameters. Conclusions We ascertained that some brain regions werecoactivated under sensory stimulation.
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