Functional Connectivity Change of the Rat Brain in Response to Sensory Stimuli Using Functional Near-Infrared Brain Imagin

Title
Functional Connectivity Change of the Rat Brain in Response to Sensory Stimuli Using Functional Near-Infrared Brain Imagin
Authors
김성우백승호송강일양세정윤인찬김법민성준경
Keywords
Diffuse optical tomography; Functional brain connectivity; Hemodynamic response
Issue Date
2014-12
Publisher
Biomedical Engineering Letters
Citation
VOL 4, 370-377
Abstract
Purpose Because the brain can divide into many separateregions structurally and these regions don’t exist independentlyin terms of their function, there are some tendencies betweenthese regions. Methods This functional connectivity has been analyzedusing functional magnetic resonance imaging (fMRI), but inrecent, diffuse optical tomography (DOT) has started toanalyze these connectivity. In our experiment, we measuredthe coactivation in brain regions in response to sensorystimulation using CW-DOT. Results Concentration changes in oxyhemoglobin anddeoxyhemoglobin was calculated using reconstructed absorptioncoefficients at each nodes in finiteelement mesh. Then thesetime-series node data were mapped on our rat brain MRimage. In addition, we analyzed coactivation by calculatingcorrelation coefficients between time-series node data andstandard response pattern of two parameters. Conclusions We ascertained that some brain regions werecoactivated under sensory stimulation.
URI
http://pubs.kist.re.kr/handle/201004/50527
ISSN
20939868
Appears in Collections:
KIST Publication > Article
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