Patterning on biodegradable nanofiber scaffold by femtosecond laser

Title
Patterning on biodegradable nanofiber scaffold by femtosecond laser
Authors
정용우전인동김유찬석현광정석전호정
Issue Date
2015-11
Publisher
대한기계학회 마이크로/나노공학부문
Abstract
Femtosecond(fs) laser has a very short pulse duration that allows to probe delicate small structures without destroying them and make material modifications on the micron scale with minimal or precisely controllable heat effects. Linear grooves and circular pits were fabricated on electrospun meshed poly-L-lactide(PLLA) by femtosecond laser patterning process. As parametric variables, pulse energy and beam spot size were varied to determine the effects on the groove and crater size. Femtosecond laser was seen to be an effective means for flexibly structuring the surface of electrospun PLLA nanofibers. As a result, the width of the groove was adjustable to 7~73 μm and the diameter of the pit was in the range of 25~54 μm. Furthermore, confluent myoblasts was cultured on the patterned electrospun fiber scaffolds to demonstrate controllable directing of myotube assembly.
URI
http://pubs.kist.re.kr/handle/201004/50583
Appears in Collections:
KIST Publication > Conference Paper
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