Isoflavones with neuroprotective activities from fruits of Cudrania tricuspidata

Title
Isoflavones with neuroprotective activities from fruits of Cudrania tricuspidata
Authors
권재영Nguyen Tuan HiepDong-Woo KimBang Yeon HwangHak-Ju LeeWoongchon MarDongho Lee
Issue Date
2015-03
Publisher
Phytochemistry
Citation
VOL 111-148
Abstract
Ten isoflavones, cudraisoflavones B-K (1-10), together with 27 known isoflavones, were isolated from the EtOAc soluble extract of fruits of Cudrania tricuspidata. The structures of compounds 1-10 were elucidated on the basis of MS and NMR spectroscopic data, including 2D NMR experiments. Compounds 7-9 and three known (11-13) compounds showed neuroprotective activity against 6-hydroxydopamine induced cell death in human neuroblastoma SH-SY5Y cells, with EC50 values of 0.5-9.2 mu M.
URI
http://pubs.kist.re.kr/handle/201004/64907
ISSN
0031-9422
Appears in Collections:
KIST Publication > Article
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE