Nanoprobes for optical bioimaging
- Nanoprobes for optical bioimaging
- 권익찬; 김세훈; 김영선; 정근수; 이용덕; 강지수; 조홍준
- Issue Date
- Optical Materials Express
- VOL 6, NO 4-1279
- Imaging nanoprobes are a group of nano-sized contrast agents devised for providing improved contrast and spatial resolution for bioimaging. Among various imaging nanoprobes, optical nanoprobes capable of monitoring biological events or progresses in the cellular and molecular levels have been developed for early detection, accurate diagnosis, and personalized image-guided treatment of diseases. The optical activities of nanoprobes can be tuned on demand for specific applications by engineering their size, surface nature, morphology, and composition. In addition, by virtue of the nanostructure, nanoprobes have displayed favorable pharmacokinetic features and target specificity reflecting clinical demands. In this review, we focus on typical approaches and recent trends in development of nanoprobe-mediated optical imaging and their potential as a clinical diagnostic modality.
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