Challenges in wide implementation of genome editing for crop improvement

Title
Challenges in wide implementation of genome editing for crop improvement
Authors
정제형서용원
Keywords
Genome editing; homologous recombination (HR); sequence specific nucleases (SSNs); crop improvement
Issue Date
2017-06
Publisher
Journal of Crop Science and Biotechnology
Citation
VOL 20, NO 2-135
Abstract
Genome editing technologies using customizable sequence specific nucleases (SSNs) enables precise genome modification in plants, which has revolutionized functional genomics research as well as crop improvement. Applicability of SSN-mediated genome editing ranges from targeted gene knockout and single base modification to multiple gene stacking into desired genomic sites. However, there are still considerable challenges in implementing genome editing technologies for practical crop improvement. Here, we briefly discuss the technological challenges, especially those associated with the delivery of SSNs and with homologous recombination-mediated genome editing, and address some promising solutions to overcome the issues.
URI
http://pubs.kist.re.kr/handle/201004/65905
ISSN
1975-9479
Appears in Collections:
KIST Publication > ETC
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