Effect of processing method on platycodin D content in Platycodon grandiflorum roots

Title
Effect of processing method on platycodin D content in Platycodon grandiflorum roots
Authors
권재영Hyaemin LeeNahyun KimJe-Hyun LeeMi Hee WooJinwoong KimYeong Shik KimDongho Lee
Keywords
Platycodon grandiflorum; Platycodi Radix; Platycodin D; HPLC?ELSD; Processing method
Issue Date
2017-09
Publisher
Archives of pharmacal research
Citation
VOL 40, NO 9-1093
Abstract
Platycodon grandiflorum root is a traditional medicine and food material rich in triterpenoid saponins. Its major constituent, platycodin D (PD), is known to have various pharmacological properties, but processing methods may influence the PD content. In this study, a fully validated HPLC-ELSD method was developed for the quantification of PD in various states of 73 P. grandiflorum root samples from East Asia, and it exhibited a marked variation of the content. Furthermore, the effects of processing procedures such as peeling and drying temperature on the PD content were investigated using UPLC-ELSD analysis, and as a result, a significant influence of processing methods such as peeling and heating of samples on the content was confirmed. Specifically, unpeeled samples that were dried at 40 A degrees C showed the greatest PD content. The obtained results could facilitate the reliable standardization of P. grandiflorum for precise authentication and efficacious applications.
URI
http://pubs.kist.re.kr/handle/201004/66239
ISSN
0253-6269
Appears in Collections:
KIST Publication > Article
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