Current status and future direction of biodegradable metallic and polymeric vascular scaffolds for next-generation stents

Title
Current status and future direction of biodegradable metallic and polymeric vascular scaffolds for next-generation stents
Authors
김수현정영미임승혁
Keywords
Coronary artery disease; Cardiovascular stents; Biodegradable metallic scaffolds; Biodegradable polymeric scaffolds; Next-generation stents
Issue Date
2017-09
Publisher
Acta Biomaterialia
Citation
VOL 60-22
Abstract
Because of the increasing incidence of coronary artery disease, the importance of cardiovascular stents has continuously increased as a treatment of this disease. Biodegradable scaffolds fabricated from polymers and metals have emerged as promising materials for vascular stents because of their biodegradability. Although such stent framework materials have shown good clinical efficacy, it is difficult to decide whether polymers or metals are better vascular scaffolds because their properties are different. Therefore, there are still obstacles in the development of biodegradable vascular scaffolds in terms of improving clinical efficacy. This review analyzes the pros and cons of current stent materials with respect to five key factors for next-generation stent and discusses methods of improvement. Furthermore, we discuss biodegradable electronic stents with electrical conductivity, which has been considered unimportant until now, and highlight electrical conductivity as a key factor in the development of next-generation stents.
URI
http://pubs.kist.re.kr/handle/201004/66453
ISSN
1742-7061
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KIST Publication > Article
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