Construction of the Azacyclic Core of Tabernaemontanine-Related Alkaloids via Tandem Reformatsky Aza-Claisen Rearrangement

Title
Construction of the Azacyclic Core of Tabernaemontanine-Related Alkaloids via Tandem Reformatsky Aza-Claisen Rearrangement
Authors
이재균서영거임창진심재훈서영준백승민
Keywords
Pictet-Spengler cyclization; carbon skeleton and stereochemistries; X-ray crystallographic structure
Issue Date
2017-02
Publisher
Journal of organic chemistry
Citation
VOL 82, NO 3-1470
Abstract
A divergent synthetic methodology for a tabernaemontanine-related alkaloid was developed. The synthetic route features practical improvements in the Pictet-Spengler cyclization for the tetrahydro-fi-carboline intermediate and an unprecedented tandem Reformatsky aza-Claisen rearrangement to create the core carbon skeleton and stereochemistries of tabernaemontanine-related alkaloids.
URI
http://pubs.kist.re.kr/handle/201004/66747
ISSN
0022-3263
Appears in Collections:
KIST Publication > Article
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE