Recent advances in biocompatible semiconductor nanocrystals for immunobiological applications

Title
Recent advances in biocompatible semiconductor nanocrystals for immunobiological applications
Authors
김광명Sitansu Sekhar Nanda김민직Georgia C. PapaefthymiouSubramanian Tamil Selvan이동기
Keywords
Quantum dots; Immunoassay; Immunosensor; Immunofluorescent imaging; Immunotherapy
Issue Date
2017-11
Publisher
Colloids and surfaces. B, Biointerfaces
Citation
VOL 159-654
Abstract
Quantum confinement in inorganic semiconductor nanocrystals produces brightly luminescent nanoparticles endowed with unique photo-physical properties, such as tunable optical properties. These have found widespread applications in nanotechnology. The ability to render such nanostructures biocompatible, while maintaining their tunable radiation in the visible range of the electromagnetic spectrum, renders them appropriate for bio-applications. Promising in vitro and in vivo diagnostic applications have been demonstrated, such as fluorescence-based detection of biological interactions, single molecule tracking, multiplexing and immunoassaying. In particular, these fluorescent inorganic semiconductor nanocrystals, generally known as quantum dots, have the potential of remarkable immunobiological applications. This review focuses on the current status of biocompatible quantum dots and their applications in immunobiology − immunosensing, immunofluorescent imaging and immunotherapy.
URI
http://pubs.kist.re.kr/handle/201004/66998
ISSN
0927-7765
Appears in Collections:
KIST Publication > ETC
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