A Seoul-Fluor-based bioprobe for lipid droplets and its application in image-based high throughput screening
- A Seoul-Fluor-based bioprobe for lipid droplets and its application in image-based high throughput screening
- 이상희; 김은하; 박승범
- Issue Date
- Chemical communications
- VOL 48, NO 17-2333
- We developed a novel fluorescent bioprobe (SF44) that can specifically visualize the cellular lipid droplets in in vitro and in vivo systems and illustrated the mechanistic rationale of its fluorogenic property. Its application to image-based high throughput screening led us to the identification of a new small-molecule modulator of lipid droplet formation.
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