Stereochemical evaluation of bis(phosphine) copper catalysts for the asymmetric alkylation of 3- bromooxindoles with a-arylated malonate esters

Title
Stereochemical evaluation of bis(phosphine) copper catalysts for the asymmetric alkylation of 3- bromooxindoles with a-arylated malonate esters
Authors
한서정Chung Whan LeeScott C. VirgilBrian M. Stoltz
Issue Date
2015-06
Publisher
Tetrahedron
Citation
VOL 71, NO 22-3670
Abstract
An improved method for the asymmetric alkylation of 3-bromooxindoles with alpha-arylated malonate esters is described. The asymmetric alkylation demonstrated was achieved up to 70% ee utilizing a copper(II) bis(phosphine) complex.
URI
http://pubs.kist.re.kr/handle/201004/67369
ISSN
0040-4020
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KIST Publication > Article
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