Electrospun Fibrous Scaffolds for Tissue Engineering: Viewpoints on Architecture and Fabrication

Title
Electrospun Fibrous Scaffolds for Tissue Engineering: Viewpoints on Architecture and Fabrication
Authors
전호정전인동한형섭James R. Edwards
Keywords
electrospinning; nanofiber scaffolds; tissue engineering; extracellular matrix-mimicking geometries
Issue Date
2018-03
Publisher
International journal of molecular sciences
Citation
VOL 19, NO 3, 745
Abstract
Electrospinning has been used for the fabrication of extracellular matrix (ECM)-mimicking fibrous scaffolds for several decades. Electrospun fibrous scaffolds provide nanoscale/microscale fibrous structures with interconnecting pores, resembling natural ECM in tissues, and showing a high potential to facilitate the formation of artificial functional tissues. In this review, we summarize the fundamental principles of electrospinning processes for generating complex fibrous scaffold geometries that are similar in structural complexity to the ECM of living tissues. Moreover, several approaches for the formation of three-dimensional fibrous scaffolds arranged in hierarchical structures for tissue engineering are also presented.
URI
http://pubs.kist.re.kr/handle/201004/67390
ISSN
1422-0067
Appears in Collections:
KIST Publication > ETC
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