Effect of various shaped magnesium hydroxide particles on mechanical and biological properties of poly(lactic-co-glycolic acid) composites
- Effect of various shaped magnesium hydroxide particles on mechanical and biological properties of poly(lactic-co-glycolic acid) composites
- 정윤기; 장혜정; 박성빈; 타렉베딜; 오민규; 안동준; 박우람; 한동근
- Issue Date
- Journal of industrial and engineering chemistry
- VOL 59-276
- Five different shapes of magnesium hydroxide (Mg(OH)(2)) particles (Plate-S, Plate-N, Disk, Whisker, and Fiber) were synthesized and added to biopolymer (i.e., Poly(lactic-co-glycolic acid) (PLGA)) composite to improve their mechanical and biological properties. The PLGA composite films including Mg(OH)(2) particles were prepared by a solvent casting method. Their mechanical and biological properties were compared according to the composites containing different shapes of Mg(OH)(2) particles. Among them; the fiber shape of Mg(OH)(2) provided the highest mechanical strength, and anti-inflammation and antibacterial activity to PLGA films among other forms. This study demonstrated a new strategy for the design of biomaterials by controlling the form of inorganic additives.
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