Death-associated protein kinase (DAPK) family modulators: Current and future therapeutic outcomes

Title
Death-associated protein kinase (DAPK) family modulators: Current and future therapeutic outcomes
Authors
노은주아메드 카람
Keywords
DAPK1; Tau protein; CNS disease
Issue Date
2019-01
Publisher
Medicinal research reviews
Citation
VOL 39, NO 1-385
Abstract
Serine/threonine kinases (STKs) represent the majority of discovered kinases to date even though a few Food and Drug Administration approved STKs inhibitors are reported. The third millennium came with the discovery of an important group of STKs that reshaped our understanding of several biological signaling pathways. This family was named death-associated protein kinase family (DAPK family). DAPKs comprise five members (DAPK1, DAPK2, DAPK3, DRAK1, and DRAK2) and belong to the calcium/calmodulindependent kinases domain. As time goes on, the list of biological functions of this family is constantly updated. The most extensively studied member is DAPK1 (based on the publications number and Protein Data Bank reported crystal structures) that plays
URI
http://pubs.kist.re.kr/handle/201004/69435
ISSN
0198-6325
Appears in Collections:
KIST Publication > ETC
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE