Stabilin Receptors: Role as Phosphatidylserine Receptors

Title
Stabilin Receptors: Role as Phosphatidylserine Receptors
Authors
김인산Seung-Yoon Park
Issue Date
2019-08
Publisher
Biomolecules
Citation
VOL 9-387-16
Abstract
Phosphatidylserine is a membrane phospholipid that is localized to the inner leaflet of the plasma membrane. Phosphatidylserine externalization to the outer leaflet of the plasma membrane is an important signal for various physiological processes, including apoptosis, platelet activation, cell fusion, lymphocyte activation, and regenerative axonal fusion. Stabilin-1 and stabilin-2 are membrane receptors that recognize phosphatidylserine on the cell surface. Here, we discuss the functions of Stabilin-1 and stabilin-2 as phosphatidylserine receptors in apoptotic cell clearance (e erocytosis) and cell fusion, and their ligand-recognition and signaling pathways.
URI
http://pubs.kist.re.kr/handle/201004/69929
ISSN
2218-273X
Appears in Collections:
KIST Publication > ETC
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