Brain-on-a-chip: A history of development and future perspective

Title
Brain-on-a-chip: A history of development and future perspective
Authors
최낙원김홍남방석영정소현
Issue Date
2019-10
Publisher
Biomicrofluidics
Citation
VOL 13-051301-7
Abstract
Since the advent of organ-on-a-chip, many researchers have tried to mimic the physiology of human tissue on an engineered platform. In the case of brain tissue, structural connections and cell– cell interactions are important factors for brain function. The recent development of brain-on-a-chip is an effort to mimic those structural and functional aspects of brain tissue within a miniaturized engineered platform. From this perspective, we provide an overview of trace of brain-on-a-chip development, especially in terms of complexity and high-content/high-throughput screening capabilities, and future perspectives on more in vivo-like brain-on-a-chip development.
URI
http://pubs.kist.re.kr/handle/201004/70082
ISSN
1932-1058
Appears in Collections:
KIST Publication > Article
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