Chiral Bicyclic Bridgehead Phosphoramidite (Briphos) Ligands for Asymmetric Rhodium-Catalyzed 1,2-and 1,4-Addition

Title
Chiral Bicyclic Bridgehead Phosphoramidite (Briphos) Ligands for Asymmetric Rhodium-Catalyzed 1,2-and 1,4-Addition
Authors
이안수Hyunwoo Kim
Issue Date
2016-04
Publisher
Journal of organic chemistry
Citation
VOL 81, NO 9-3527
Abstract
A complementary solution for Rh-catalyzed enantioselective 1,2- and 1,4-arylation with two structurally related chiral ligands is reported. A chiral bicyclic bridgehead phosphoramidite (briphos) ligand.derived from 1-aminoindane was efficient for the 1,2-arylation of N-sulfonyl imines, while that derived from 1,2,3,4-tetrahydro-1-naphthylamine was efficient for 1,4-arylation of alpha,beta-unsaturated cyclic ketones. For alpha,beta-unsaturated N-tosyl ketimines, the briphos derived from 1-aminoindane was found to selectively provide gamma,gamma-diaryl N-tosyl enamines with high yields and stereoselectivities.
URI
http://pubs.kist.re.kr/handle/201004/70409
ISSN
0022-3263
Appears in Collections:
KIST Publication > Article
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE