Applications of Converged Various Forces for Detection of Biomolecules and Novelty of Dielectrophoretic Force in the Applications
- Applications of Converged Various Forces for Detection of Biomolecules and Novelty of Dielectrophoretic Force in the Applications
- 이병철; Seungjun Lee; Seong Min Roh; Eunji Lee; Yejin Park; Youngeun Kwon; Hye Jin Kim; Jinsik Kim
- biomolecule separation; dielectrophoresis; electrophoresis; acoustophoretic; electroosmotic flow force; magnetophoretic force; electrokinetic force; hydrodynamic force; optical trapping force
- Issue Date
- VOL 20, NO 11-18
- Since separation of target biomolecules is a crucial step for highly sensitive and selective detection of biomolecules, hence, various technologies have been applied to separate biomolecules, such as deoxyribonucleic acid (DNA), protein, exosome, virus, etc. Among the various technologies, dielectrophoresis(DEP)hasthesigniﬁ cantadvantagethattheforcecanprovidetwodiﬀ erenttypesof forces, attractive and repulsive DEP force, through simple adjustment in frequency or structure of microﬂ uidic chips. Therefore, in this review, we focused on separation technologies based on DEP force and classiﬁ ed various separation technologies. First, the importance of biomolecules, general separationmethodsandvariousforcesincludingDEP,electrophoresis(EP),electrothermalﬂ ow(ETF), electroosmosis (EO), magnetophoresis, acoustophoresis (ACP), hydrodynamic, etc., was described. Then, separating technologies applying only a single DEP force and dual force, moreover, applying other forces simultaneously with DEP force were categorized. In addition, advanced technologies applying more than two diﬀ erent kinds of forces, namely complex force, were introduced. Overall, we critically reviewed the state-of-the-art of converged various forces for detection of biomolecules with novelty of DEP.
- Appears in Collections:
- KIST Publication > Article
- Files in This Item:
There are no files associated with this item.
- RIS (EndNote)
- XLS (Excel)
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.