Browsing by Author 허우영

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Showing results 1 to 30 of 41

Issue DateTitleAuthor(s)
2020-07-312,3,5-치환된 싸이오펜 화합물의 비만세포증 예방, 개선 또는 치료 용도남기엽; 송치만; 심태보; 윤정혁; 조한나; 최승혜; 허우영
2020-07-312,3,5-치환된 싸이오펜 화합물의 위장관기질종양 예방, 개선 또는 치료 용도김남경; 남기엽; 송치만; 심태보; 윤정혁; 조한나; 최승혜; 허우영
2017-01A benzo[b]thiophene-based selective type 4 S1P receptor agonistNathanael S. Gray; 허우영; Hugh Rosen
2014-11A Discovery Strategy for Selective Inhibitors of c-Src in Complex with the Focal Adhesion Kinase SH3/SH2-binding RegionJamie A. Moroco; Matthew P. Baumgartner; Heather L. Rust; Hwan Geun Choi; 허우영; Nathanael S. Gray; Carlos J. Camacho; Thomas E. Smithgall
2013-10A novel small molecule inducer of cellular antioxidant response허우영
2010-05A Small-Molecule Inducer of the Antioxidant Response Element허우영; Zheng Sun; Tao Jiang; Daniel E. Mason; Eric C. Peters; Donna D. Zhang; Hendrik Luesch; Peter G. Schultz; Nathanael S. Gray
2010-03A Structure-Guided Approach to Creating Covalent FGFR InhibitorsWenjun Zhou; 허우영; Ultan McDermott; Amit Dutt; Wa Xian; Scott B. Ficarro; Jianming Zhang; Sreenath V. Sharma; Joan Brugge; Matthew Meyerson; Jeffrey Settleman; Nathanael S. Gray
2006-02Allosteric inhibitors of Bcr-abl-dependent cell proliferationFrancisco J Adrian; Qiang Ding; Taebo Sim; Anastasia Velentza; Christine Sloan; Yi Liu; Guobao Zhang; 허우영; Sheng Ding; Paul Manley; Jurgen Mestan; Doriano Fabbro; Nathanael S Gray
2018-02Amphiphilic small peptides for delivery of plasmid DNAs and siRNAs심태보; 허우영; 방은경; 나 리 트란; 조한나; 전성훈; 임동권
2015-10Antitumor Effects and Mechanisms of AZD4547 on FGFR2-Deregulated Endometrial Cancer Cells곽연의; 조한나; 허우영; 심태보
2013-04Characterization of Torin2, an ATP-competitive inhibitor of mTOR, ATM, and ATRQingsong Liu; Chunxiao Xu; Sivapriya Kirubakaran; Xin Zhang; 허우영; Yan Liu; Nicholas P. Kwiatkowski; Jinhua Wang; Kenneth D. Westover; Peng Gao; Dalia Ercan; Mario Niepel; Carson C. Thoreen; Seong A. Kang; Matthew P. Patricelli; Yuchuan Wang; Tanya Tupper; Abigail Altabef; Hidemasa Kawamura; Kathryn D. Held; Danny M. Chou; Stephen J. Elledge; Pasi A. Janne; Kwok-Kin Wong; David M. Sabatini; Nathanael S. Gray
2008-07Clinical stage EGFR inhibitors irreversibly alkylate Bmx kinase허우영; Anastasia Velentza; Sungjoon Kim; Laura Flatauer; Xinnong Jiang; David Valente; Daniel E. Mason; Melissa Suzuki; Brad Larson; Jianming Zhang; Anna Zagorska; Michael DiDonato; Advait Nagle; Markus Warmuth; Steven P. Balk; Eric C. Peters; Nathanael S. Gray
2018-09Design, synthesis and biological evaluation of novel thiazolidinedione derivatives as irreversible allosteric IKK-β modulators노은주; 허우영; 김남윤; 박정은; Elkamhawy Ahmed; Ahmed H.E. Hassan; 양정은; 오광석; 이병호; 이미영; 신계정; 이경태
2018-12Design, synthesis, and biological evaluation of novel aminopyrimidinylisoindolines as AXL kinase inhibitors유경호; 오창현; 이소하; 노은주; 심태보; 허우영; 최민정; 이선화; 김종승
2012-09Development of ATP-Competitive mTOR Inhibitors허우영; Qingsong Liu; Seong A. Kang; Carson C. Thoreen; Jinhua Wang; Jae Won Chang; Andrew Markhard; Jianming Zhang; Taebo Sim; David M. Sabatini; Nathanael S. Gray
2014-11Development of covalent inhibitors that can overcome resistance to first-generation FGFR kinase inhibitorsLi Tan; Jun Wang; Junko Tanizaki; Zhifeng Huang; Amir R. Aref; Maria Rusan; Su-Jie Zhu; Yiyun Zhang; Dalia Ercan; Rachel G. Liao; Marzia Capelletti; Wenjun Zhou; 허우영; NamDoo Kim; 심태보; Suzanne Gaudet; David A. Barbie; Jing-Ruey Joanna Yeh; Cai-Hong Yun; Peter S. Hammerman; Moosa Mohammadi; Pasi A. Janne; Nathanael S. Gray
2011-05Discovery and optimization of potent and selective benzonaphthyridinone analogs as small molecule mTOR inhibitors with improved mouse microsome stabilityQingsong Liu; Jinhua Wang; Seong A. Kang; Carson C. Thoreen; 허우영; Hwan Geun Choi; David L. Waller; Taebo Sim; David M. Sabatini; Nathanael S. Gray
2010-09Discovery of 1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one as a Highly Potent, Selective Mammalian Target of Rapamycin (mTOR) Inhibitor for the Treatment of CancerQingsong Liu; Jae Won Chang; Jinhua Wang; Seong A. Kang; Carson C. Thoreen; Andrew Markhard; 허우영; Jianming Zhang; Taebo Sim; David M. Sabatini; Nathanael S. Gray
2011-02Discovery of 9-(6-Aminopyridin-3-yl)-1-(3-(trifluoromethyl)-phenyl)benzo[h][1,6]naphthyridin-2(1H)-one (Torin2) as a Potent, Selective, and Orally Available Mammalian Target of Rapamycin (mTOR) Inhibitor for Treatment of CancerQingsong Liu; Jinhua Wang; Seong A. Kang; Carson C. Thoreen; 허우영; Tausif Ahmed; David M. Sabatini; Nathanael S. Gray
2013-04Discovery of a Selective Irreversible BMX Inhibitor for Prostate CancerFeiyang Liu; Xin Zhang; Ellen Weisberg; Sen Chen; 허우영; Hong Wu; Zheng Zhao; Wenchao Wang; Mao Mao; Changmeng Cai; Nicholas I. Simon; Takaomi Sanda; Jinhua Wang; A. Thomas Look; James D. Griffin; Steven P. Balk; Qingsong Liu; Nathanael S. Gray
2006-02Discovery of EGFR Selective 4,6-Disubstituted Pyrimidines from a Combinatorial Kinase-Directed Heterocycle LibraryQiong Zhang; Yi Liu; Feng Gao; Qiang Ding; Charles Cho; 허우영; Yunho Jin; Tetsuo Uno; Claudio A. P. Joazeiro; Nathanael Gray
2018-09First SAR Study for Overriding NRAS Mutant Driven Acute Myeloid심태보; 허우영; 최승혜; 조한나; 신인재; Eunhye Ju; Haelee Kim; Eunmi Hong; Nam Doo Kim; Hwan Geun Choi; Nathanael S. Gray
2016-10Identification and chracterization of novel small molecule suppressor and inducer of intracellular reactive oxygen species as a potential neuroprotective agent and a potential anticancer agent허우영
2020-03Identification of a Novel Oxadiazole Inhibitor of Mammalian Target of Rapamycin허우영; 임선우; 김의정; 이효민
2015-05Identification of Novel ROS Inducers: Quinone Derivatives Tethered to Long Hydrocarbon Chains홍연선; Sandip Sengupta; 허우영; 심태보
2017-04Identification of TG100-115 as a new and potent TRPM7 kinase inhibitor, which suppresses breast cancer cell migration and invasion심태보; 송치만; 허우영; 이효민; 배연주; 전진주; 김남두; 이경복; 박재용
2017-02Identification of the First Selective Activin Receptor-Like Kinase 1 Inhibitor, a Reversible Version of L-783277심태보; 허우영; 최환근; 전성훈; 조한나; Sandip Sengupta; 서홍석; 이병우; 김정훈; 정민환; 전누리; 김남두
2012-03Kinome-wide Selectivity Profiling of ATP-competitive Mammalian Target of Rapamycin (mTOR) Inhibitors and Characterization of Their Binding KineticsQingsong Liu; Sivapriya Kirubakaran; 허우영; Mario Niepel; Kenneth Westover; Carson C. Thoreen; Jinhua Wang; Jing Ni; Matthew P. Patricelli; Kurt Vogel; Steve Riddle; David L. Waller; Ryan Traynor; Takaomi Sanda; Zheng Zhao; Seong A. Kang; Jean Zhao; A. Thomas Look; Peter K. Sorger; David M. Sabatini; Nathanael S. Gray
2013-12Nrf2 활성화를 통한 세포내 항산화 반응을 일으키는 화합물허우영
2014-12Patient-derived models of acquired resistance can identify effective drug combinations for cancerAdam S. Crystal; Alice T. Shaw; Lecia V. Sequist; Luc Friboulet; Matthew J. Niederst; Elizabeth L. Lockerman; Rosa L. Frias; Justin F. Gainor; Arnaud Amzallag; Patricia Greninger; Dana Lee; Anuj Kalsy; Maria Gomez-Caraballo; Leila Elamine; Emily Howe; 허우영; Eugene Lifshits; Hayley E. Robinson; Ryohei Katayama; Anthony C. Faber; Mark M. Awad; Sridhar Ramaswamy; Mari Mino-Kenudson; A. John Iafrate; Cyril H. Benes; Jeffrey A. Engelman

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