Showing results 1 to 30 of 70
Issue Date | Title | Author(s) |
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2020-12-15 | 2-Anilinoquinoline based arylamides as broad spectrum anticancer agents with B-RAF(V600E)/C-RAF kinase inhibitory effects: Design, synthesis, in vitro cell-based and oncogenic kinase assessments | El-Damasy, Ashraf K.; Haque, Md Mamunul; Park, Jung Woo; Shin, Sang Chul; Lee, Jun-Seok; Kim, Eunice EunKyeong; Keum, Gyochang |
2024-08 | A lipid nanoparticle platform incorporating trehalose glycolipid for exceptional mRNA vaccine safety | Bae, Seo-Hyeon; Soyeon Yoo; Lee, Jisun; Park, Hyo-Jung; Sung Pil Kwon; Jin, Harin; Park, Sang-In; Lee, Yu-Sun; Bang, Yoo-Jin; Roh, Gahyun; Lee, Seonghyun; Youn, Sue Bean; Kim, In Woo; Oh, Ho Rim; Ashraf kareem; Keum, Gyochang; Kim, Hojun; Youn, Hyewon; Nam, Jae-Hwan; Bang, Eun-Kyoung |
2018-07 | A novel tropomyosin-related kinase A inhibitor, KK5101 to treat pancreatic cancer | Fang, Zhenghuan; Han, Boreum; Jung, Kyung Hee; Lee, Ju-Hyeon; El-Damasy, Ashraf Kareem; Gadhe, Changdev G.; Kim, Soo Jung; Yan, Hong Hua; Park, Jung Hee; Lee, Ji Eun; Kang, Yeo Wool; Pae, Ae Nim; Keum, Gyochang; Hong, Soon-Sun |
2015-05-15 | ABL kinase inhibitory and antiproliferative activity of novel picolinamide based benzothiazoles | El-Damasy, Ashraf Kareem; Cho, Nam-Chul; Kang, Soon Bang; Pae, Ae Nim; Keum, Gyochang |
2003-09 | An efficient synthesis of 2,5-diketopiperazine derivatives by the Ugi four-center three-component reaction | Cho, Sangwon; Keum, Gyochang; Kang, Soon Bang; Han, So-Yeop; Kim, Youseung |
2024-05 | Analysis of the Immunostimulatory Effects of Cytokine-Expressing Internal Ribosome Entry Site-Based RNA Adjuvants and Their Applications | Lee, Yu-Sun; Bang, Yoo-Jin; Yoo, Soyeon; Park, Sang-In; Park, Hyo-Jung; Kwak, Hye Won; Bae, Seo-Hyeon; Park, Hyeong-Jun; Kim, Jae-Yong; Youn, Sue-Bean; Roh, Gahyun; Lee, Seonghyun; Kwon, Sung Pil; Bang, Eun-Kyoung; Keum, Gyochang; Nam, Jae-Hwan; Hong, So-Hee |
2023-06 | Analyzing immune responses to varied mRNA and protein vaccine sequences | Park, Hyeong-Jun; Bang, Yoo-Jin; Kwon, Sung Pil; Kwak, Woori; Park, Sang-In; Roh, Gahyun; Bae, Seo-Hyeon; Kim, Jae-Yong; Kwak, Hye Won; Kim, Yongkwan; Yoo, Soyeon; Kim, Daegeun; Keum, Gyochang; Bang, Eun-Kyoung; Hong, So-Hee; Nam, Jae-Hwan |
2013-11 | Aryl Biphenyl-3-ylmethylpiperazines as 5-HT7 Receptor Antagonists | Kim, Jeeyeon; Kim, Youngjae; Tae, Jinsung; Yeom, Miyoung; Moon, Bongjin; Huang, Xi-Ping; Roth, Bryan L.; Lee, Kangho; Rhim, Hyewhon; Choo, Il Han; Chong, Youhoon; Keum, Gyochang; Nam, Ghilsoo; Choo, Hyunah |
2015-02 | Chemo- and Stereoselective Reduction of beta-Keto-alpha-oximino Nitriles by Using Baker's Yeast | Mo, Kilwoong; Kang, Soon Bang; Kim, Youseung; Lee, Yong Sup; Lee, Jae Wook; Keum, Gyochang |
2016-08 | Coordinative Amphiphiles as Tunable siRNA Transporters | Kim, Jin Bum; Lee, Yeong Mi; Ryu, Jooyeon; Lee, Eunji; Kim, Won Jong; Keum, Gyochang; Bang, Eun-Kyoung |
2017-01 | Design and synthesis of new 2-anilinoquinolines bearing N-methylpicolinamide moiety as potential antiproliferative agents | El-Damasy, Ashraf Kareem; Seo, Seon Hee; Cho, Nam-Chul; Pae, Ae Nim; Kim, Eunice Eunkyeong; Keum, Gyochang |
2023-06 | Design and Synthesis of New 4-(3,4,5-Trimethoxyphenyl)Thiazole-Pyrimidine Derivatives as Potential Antiproliferative Agents | El-Damasy, Ashraf K.; Jin, Heewon; Sabry, Mohamed A.; Kim, Hyun Ji; Alanazi, Mohammed M.; Seo, Seon Hee; Bang, Eun-Kyoung; Keum, Gyochang |
2016-06-10 | Design and synthesis of new potent anticancer benzothiazole amides and ureas featuring pyridylamide moiety and possessing dual B-Raf(V600E) and C-Raf kinase inhibitory activities | El-Damasy, Ashraf Kareem; Lee, Ju-Hyeon; Seo, Seon Hee; Cho, Nam-Chul; Pae, Ae Nim; Keum, Gyochang |
2020-12-01 | Design, synthesis, and biological evaluations of novel 3-amino-4-ethynyl indazole derivatives as Bcr-Abl kinase inhibitors with potent cellular antileukemic activity | El-Damasy, Ashraf K.; Jin, Heewon; Seo, Seon Hee; Bang, Eun-Kyoung; Keum, Gyochang |
2015-08 | Design, synthesis, in-vitro antiproliferative activity and kinase profile of new picolinamide based 2-amido and ureido quinoline derivatives | El-Damasy, Ashraf Kareem; Seo, Seon Hee; Cho, Nam-Chul; Kang, Soon Bang; Pae, Ae Nim; Kim, Key-Sun; Keum, Gyochang |
2014-05-03 | Determination of Edible Vegetable Oil Adulterants in Sesame Oil Using H-1 Nuclear Magnetic Resonance Spectroscopy | Nam, Yun Sik; Noh, Kown-Chul; Roh, Eun Joo; Keum, Gyochang; Lee, Yeonhee; Lee, Kang-Bong |
2012-10-09 | Dicyanovinylnaphthalenes for neuroimaging of amyloids and relationships of electronic structures and geometries to binding affinities | Petric, Andrej; Johnson, Scott A.; Pham, Hung V.; Li, Ying; Ceh, Simon; Golobic, Amalija; Agdeppa, Eric D.; Timbol, Gerald; Liu, Jie; Keum, Gyochang; Satyamurthy, Nagichettiar; Kepe, Vladimir; Houk, Kendall N.; Barrio, Jorge R. |
2015-06-05 | Discovery and biological evaluation of tetrahydrothieno[2,3-c]pyridine derivatives as selective metabotropic glutamate receptor 1 antagonists for the potential treatment of neuropathic pain | Nam, Mina; Kim, TaeHun; Kwak, Jinsook; Seo, Seon Hee; Ko, Min Kyung; Lim, Eun Jeong; Min, Sun-Joon; Cho, Yong Seo; Keum, Gyochang; Baek, Du-Jong; Lee, Jiyoun; Pae, Ae Nim |
2013-08 | Discovery and development of heat shock protein 90 inhibitors as anticancer agents: a review of patented potent geldanamycin derivatives | Kim, TaeHun; Keum, Gyochang; Pae, Ae Nim |
2016-08-05 | Discovery of a Nanomolar Multikinase Inhibitor (KST016366): A New Benzothiazole Derivative with Remarkable Broad-Spectrum Antiproliferative Activity | El-Damasy, Ashraf Kareem; Cho, Nam-Chul; Nam, Ghilsoo; Pae, Ae Nim; Keum, Gyochang |
2013-05-01 | Discovery of aryl-biphenyl-2-ylmethylpiperazines as novel scaffolds for 5-HT7 ligands and role of the aromatic substituents in binding to the target receptor | Kim, Youngjae; Kim, Jeeyeon; Tae, Jinsung; Roth, Bryan L.; Rhim, Hyewhon; Keum, Gyochang; Nam, Ghilsoo; Choo, Hyunah |
2021-09 | Discovery of G Protein-Biased Antagonists against 5-HT7R | Kwag, Rina; Lee, Jieon; Kim, Doyoung; Lee, Haeun; Yeom, Miyoung; Woo, Jiwan; Cho, Yakdol; Kim, Hak Joong; Kim, Jeongjin; Keum, Gyochang; Jeon, Byungsun; Choo, Hyunah |
2023-02 | Discovery of new 6-ureido/amidocoumarins as highly potent and selective inhibitors for the tumour-relevant carbonic anhydrases IX and XII | 아쉬라프 카림; Kim Hyun Ji; Nocentini, Alessio; Seo, Seon Hee; Eldehna, Wagdy M.; Bang, Eun-Kyoung; Supuran, Claudiu T.; Keum, Gyochang |
2023-02 | Discovery of New Quinolone-Based Diarylamides as Potent B-RAFV600E/C-RAF Kinase Inhibitors Endowed with Promising In Vitro Anticancer Activity | Kim Hyun Ji; Park, Jung Woo; Seo, Sangjae; Cho, Kwang-Hwi; Alanazi, Mohammed M.; Bang, Eun Kyoung; Keum, Gyochang; Ashraf kareem |
2024-02 | Discovery of thiophen-2-ylmethylene bis-dimedone derivatives as novel WRN inhibitors for treating cancers with microsatellite instability | Hwasun Yang; Kang, Miso; Jang, Seonyeong; Soo Yeon Baek; Kim, Jiwon; Gyeongun Kim; Kim, Dongwoo; Ha, Junsu; Seung Kim, Jong; Jung, Cheulhee; Kim, Nam-Jung; Cho, Sung-Yup; Shin, Woong-Hee; Lee, Juyong; Ko, Junsu; Lee, Ansoo; Keum, Gyochang; Lee, Sang hee; Kang, Taek |
2014-08-14 | Efficient synthesis of mibefradil analogues: an insight into in vitro stability | Lee, Ji Eun; Kwon, Tae Hui; Gu, Su Jin; Lee, Duck-Hyung; Kim, B. Moon; Lee, Jae Yeol; Lee, Jae Kyun; Seo, Seon Hee; Pae, Ae Nim; Keum, Gyochang; Cho, Yong Seo; Min, Sun-Joon |
2014-12 | Facile diverted synthesis of pyrrolidinyl triazoles using organotrifluoroborate: discovery of potential mPTP blockers | Jung, Sun Hwa; Choi, Kihang; Pae, Ae Nim; Lee, Jae Kyun; Choo, Hyunah; Keum, Gyochang; Cho, Yong Seo; Min, Sun-Joon |
2024-03 | Identification of an Antagonist Targeting G Protein and β-Arrestin Signaling Pathways of 5-HT7R | Jeong, Jeong Hyun; Lee, Haeun; Doyoung Kim; Park, Eunseo; Woo, Jiwan; Yakdol, Cho; Keum, Gyochang; Lee, Ansoo; Kang, Taek; Kim, Jeongjin; Choo, Hyunah; Lee, Sanghee; Jeon, Byungsun |
2023-01 | Identification of New N-methyl-piperazine Chalcones as Dual MAO-B/AChE Inhibitors | Ashraf kareem; Park, Jong Eun; Kim Hyun Ji; Lee, Jinhyuk; Bang, Eun-Kyoung; Kim, Hoon; Keum, Gyochang |
2025-01 | Immunogenicity and Protection of a Triple Repeat Domain Iii Mrna Vaccine Against Zika Virus | Lee, Yu-Sun; Cheong, Mi Sun; Lee, Jisun; Bang, Eun-Kyoung; Park, Sang In; Park, Hyo-Jung; Bae, Seo-Hyeon; Youn, Sue Bean; Roh, Gahyun; Lee, Seonghyun; Cho, Youngran; Ha, Dahyeon; Oh, Ayoung; Lee, Soo-Yeon; Choi, Eun-Jin; Choi, Huijeong; Jo, Sohee; Lee, Yeeun; Kim, Jungmin; Kawk, Hye Won; Bang, Yoo-Jin; Lee, Dabin; Shim, Heeyoun; Park, Young K.; Keum, Gyochang; Nam, Jae-Hwan; kim, Wonil |