Browsing byAuthorKeum, Gyochang

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Showing results 1 to 30 of 68

Issue DateTitleAuthor(s)
2020-12-152-Anilinoquinoline based arylamides as broad spectrum anticancer agents with B-RAF(V600E)/C-RAF kinase inhibitory effects: Design, synthesis, in vitro cell-based and oncogenic kinase assessmentsEl-Damasy, Ashraf K.; Haque, Md Mamunul; Park, Jung Woo; Shin, Sang Chul; Lee, Jun-Seok; Kim, Eunice EunKyeong; Keum, Gyochang
2024-08A lipid nanoparticle platform incorporating trehalose glycolipid for exceptional mRNA vaccine safetyBae, Seo-Hyeon; Soyeon Yoo; Lee, Jisun; Park, Hyo-Jung; Sung Pil Kwon; Jin, Harin; Park, Sang-In; Lee, Yu-Sun; Bang, Yoo-Jin; Roh, Gahyun; Lee, Seonghyun; Youn, Sue Bean; Kim, In Woo; Oh, Ho Rim; Ashraf kareem; Keum, Gyochang; Kim, Hojun; Youn, Hyewon; Nam, Jae-Hwan; Bang, Eun-Kyoung
2018-07A novel tropomyosin-related kinase A inhibitor, KK5101 to treat pancreatic cancerFang, Zhenghuan; Han, Boreum; Jung, Kyung Hee; Lee, Ju-Hyeon; El-Damasy, Ashraf Kareem; Gadhe, Changdev G.; Kim, Soo Jung; Yan, Hong Hua; Park, Jung Hee; Lee, Ji Eun; Kang, Yeo Wool; Pae, Ae Nim; Keum, Gyochang; Hong, Soon-Sun
2015-05-15ABL kinase inhibitory and antiproliferative activity of novel picolinamide based benzothiazolesEl-Damasy, Ashraf Kareem; Cho, Nam-Chul; Kang, Soon Bang; Pae, Ae Nim; Keum, Gyochang
2003-09An efficient synthesis of 2,5-diketopiperazine derivatives by the Ugi four-center three-component reactionCho, Sangwon; Keum, Gyochang; Kang, Soon Bang; Han, So-Yeop; Kim, Youseung
2024-05Analysis of the Immunostimulatory Effects of Cytokine-Expressing Internal Ribosome Entry Site-Based RNA Adjuvants and Their ApplicationsLee, Yu-Sun; Bang, Yoo-Jin; Yoo, Soyeon; Park, Sang-In; Park, Hyo-Jung; Kwak, Hye Won; Bae, Seo-Hyeon; Park, Hyeong-Jun; Kim, Jae-Yong; Youn, Sue-Bean; Roh, Gahyun; Lee, Seonghyun; Kwon, Sung Pil; Bang, Eun-Kyoung; Keum, Gyochang; Nam, Jae-Hwan; Hong, So-Hee
2023-06Analyzing immune responses to varied mRNA and protein vaccine sequencesPark, Hyeong-Jun; Bang, Yoo-Jin; Kwon, Sung Pil; Kwak, Woori; Park, Sang-In; Roh, Gahyun; Bae, Seo-Hyeon; Kim, Jae-Yong; Kwak, Hye Won; Kim, Yongkwan; Yoo, Soyeon; Kim, Daegeun; Keum, Gyochang; Bang, Eun-Kyoung; Hong, So-Hee; Nam, Jae-Hwan
2013-11Aryl Biphenyl-3-ylmethylpiperazines as 5-HT7 Receptor AntagonistsKim, Jeeyeon; Kim, Youngjae; Tae, Jinsung; Yeom, Miyoung; Moon, Bongjin; Huang, Xi-Ping; Roth, Bryan L.; Lee, Kangho; Rhim, Hyewhon; Choo, Il Han; Chong, Youhoon; Keum, Gyochang; Nam, Ghilsoo; Choo, Hyunah
2015-02Chemo- and Stereoselective Reduction of beta-Keto-alpha-oximino Nitriles by Using Baker's YeastMo, Kilwoong; Kang, Soon Bang; Kim, Youseung; Lee, Yong Sup; Lee, Jae Wook; Keum, Gyochang
2016-08Coordinative Amphiphiles as Tunable siRNA TransportersKim, Jin Bum; Lee, Yeong Mi; Ryu, Jooyeon; Lee, Eunji; Kim, Won Jong; Keum, Gyochang; Bang, Eun-Kyoung
2017-01Design and synthesis of new 2-anilinoquinolines bearing N-methylpicolinamide moiety as potential antiproliferative agentsEl-Damasy, Ashraf Kareem; Seo, Seon Hee; Cho, Nam-Chul; Pae, Ae Nim; Kim, Eunice Eunkyeong; Keum, Gyochang
2023-06Design and Synthesis of New 4-(3,4,5-Trimethoxyphenyl)Thiazole-Pyrimidine Derivatives as Potential Antiproliferative AgentsEl-Damasy, Ashraf K.; Jin, Heewon; Sabry, Mohamed A.; Kim, Hyun Ji; Alanazi, Mohammed M.; Seo, Seon Hee; Bang, Eun-Kyoung; Keum, Gyochang
2016-06-10Design and synthesis of new potent anticancer benzothiazole amides and ureas featuring pyridylamide moiety and possessing dual B-Raf(V600E) and C-Raf kinase inhibitory activitiesEl-Damasy, Ashraf Kareem; Lee, Ju-Hyeon; Seo, Seon Hee; Cho, Nam-Chul; Pae, Ae Nim; Keum, Gyochang
2020-12-01Design, synthesis, and biological evaluations of novel 3-amino-4-ethynyl indazole derivatives as Bcr-Abl kinase inhibitors with potent cellular antileukemic activityEl-Damasy, Ashraf K.; Jin, Heewon; Seo, Seon Hee; Bang, Eun-Kyoung; Keum, Gyochang
2015-08Design, synthesis, in-vitro antiproliferative activity and kinase profile of new picolinamide based 2-amido and ureido quinoline derivativesEl-Damasy, Ashraf Kareem; Seo, Seon Hee; Cho, Nam-Chul; Kang, Soon Bang; Pae, Ae Nim; Kim, Key-Sun; Keum, Gyochang
2014-05-03Determination of Edible Vegetable Oil Adulterants in Sesame Oil Using H-1 Nuclear Magnetic Resonance SpectroscopyNam, Yun Sik; Noh, Kown-Chul; Roh, Eun Joo; Keum, Gyochang; Lee, Yeonhee; Lee, Kang-Bong
2012-10-09Dicyanovinylnaphthalenes for neuroimaging of amyloids and relationships of electronic structures and geometries to binding affinitiesPetric, Andrej; Johnson, Scott A.; Pham, Hung V.; Li, Ying; Ceh, Simon; Golobic, Amalija; Agdeppa, Eric D.; Timbol, Gerald; Liu, Jie; Keum, Gyochang; Satyamurthy, Nagichettiar; Kepe, Vladimir; Houk, Kendall N.; Barrio, Jorge R.
2015-06-05Discovery and biological evaluation of tetrahydrothieno[2,3-c]pyridine derivatives as selective metabotropic glutamate receptor 1 antagonists for the potential treatment of neuropathic painNam, Mina; Kim, TaeHun; Kwak, Jinsook; Seo, Seon Hee; Ko, Min Kyung; Lim, Eun Jeong; Min, Sun-Joon; Cho, Yong Seo; Keum, Gyochang; Baek, Du-Jong; Lee, Jiyoun; Pae, Ae Nim
2013-08Discovery and development of heat shock protein 90 inhibitors as anticancer agents: a review of patented potent geldanamycin derivativesKim, TaeHun; Keum, Gyochang; Pae, Ae Nim
2016-08-05Discovery of a Nanomolar Multikinase Inhibitor (KST016366): A New Benzothiazole Derivative with Remarkable Broad-Spectrum Antiproliferative ActivityEl-Damasy, Ashraf Kareem; Cho, Nam-Chul; Nam, Ghilsoo; Pae, Ae Nim; Keum, Gyochang
2013-05-01Discovery of aryl-biphenyl-2-ylmethylpiperazines as novel scaffolds for 5-HT7 ligands and role of the aromatic substituents in binding to the target receptorKim, Youngjae; Kim, Jeeyeon; Tae, Jinsung; Roth, Bryan L.; Rhim, Hyewhon; Keum, Gyochang; Nam, Ghilsoo; Choo, Hyunah
2021-09Discovery of G Protein-Biased Antagonists against 5-HT7RKwag, Rina; Lee, Jieon; Kim, Doyoung; Lee, Haeun; Yeom, Miyoung; Woo, Jiwan; Cho, Yakdol; Kim, Hak Joong; Kim, Jeongjin; Keum, Gyochang; Jeon, Byungsun; Choo, Hyunah
2023-02Discovery of new 6-ureido/amidocoumarins as highly potent and selective inhibitors for the tumour-relevant carbonic anhydrases IX and XII아쉬라프 카림; Kim Hyun Ji; Nocentini, Alessio; Seo, Seon Hee; Eldehna, Wagdy M.; Bang, Eun-Kyoung; Supuran, Claudiu T.; Keum, Gyochang
2023-02Discovery of New Quinolone-Based Diarylamides as Potent B-RAFV600E/C-RAF Kinase Inhibitors Endowed with Promising In Vitro Anticancer ActivityKim Hyun Ji; Park, Jung Woo; Seo, Sangjae; Cho, Kwang-Hwi; Alanazi, Mohammed M.; Bang, Eun Kyoung; Keum, Gyochang; Ashraf kareem
2024-02Discovery of thiophen-2-ylmethylene bis-dimedone derivatives as novel WRN inhibitors for treating cancers with microsatellite instabilityHwasun Yang; Kang, Miso; Jang, Seonyeong; Soo Yeon Baek; Kim, Jiwon; Gyeongun Kim; Kim, Dongwoo; Ha, Junsu; Seung Kim, Jong; Jung, Cheulhee; Kim, Nam-Jung; Cho, Sung-Yup; Shin, Woong-Hee; Lee, Juyong; Ko, Junsu; Lee, Ansoo; Keum, Gyochang; Lee, Sang hee; Kang, Taek
2014-08-14Efficient synthesis of mibefradil analogues: an insight into in vitro stabilityLee, Ji Eun; Kwon, Tae Hui; Gu, Su Jin; Lee, Duck-Hyung; Kim, B. Moon; Lee, Jae Yeol; Lee, Jae Kyun; Seo, Seon Hee; Pae, Ae Nim; Keum, Gyochang; Cho, Yong Seo; Min, Sun-Joon
2014-12Facile diverted synthesis of pyrrolidinyl triazoles using organotrifluoroborate: discovery of potential mPTP blockersJung, Sun Hwa; Choi, Kihang; Pae, Ae Nim; Lee, Jae Kyun; Choo, Hyunah; Keum, Gyochang; Cho, Yong Seo; Min, Sun-Joon
2024-03Identification of an Antagonist Targeting G Protein and β-Arrestin Signaling Pathways of 5-HT7RJeong, Jeong Hyun; Lee, Haeun; Doyoung Kim; Park, Eunseo; Woo, Jiwan; Yakdol, Cho; Keum, Gyochang; Lee, Ansoo; Kang, Taek; Kim, Jeongjin; Choo, Hyunah; Lee, Sanghee; Jeon, Byungsun
2023-01Identification of New N-methyl-piperazine Chalcones as Dual MAO-B/AChE InhibitorsAshraf kareem; Park, Jong Eun; Kim Hyun Ji; Lee, Jinhyuk; Bang, Eun-Kyoung; Kim, Hoon; Keum, Gyochang
2016-07Isoxazoline, Isoxazole, and Oxadiazole Derivatives as M-1 Muscarinic Acetylcholine Receptor AgonistsMuthusamy, Selvaraj; Lee, Soo Min; Huang, Minghua; Cho, Nam-Chul; Nam, Ghilsoo; Pae, Ae Nim; Rhim, Hyewhon; Keum, Gyochang; Choi, Kyung Il

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