Kaveti, Rajaram Lee, Joong Hoon Youn, Joong Kee Jang, Tae-Min Han, Won Bae Yang, Seung Min Shin, Jeong-Woong Ko, Gwan-Jin Kim, Dong-Je Han, Sungkeun Kang, Heeseok Bandodkar, Amay J. Kim, Hyun-Young Hwang, Suk-Won 2024-01-19T08:32:58Z 2024-01-19T08:32:58Z 2024-01-11 2024-03 0935-9648 https://pubs.kist.re.kr/handle/201004/113252 Current research in the area of surgical mesh implants is somewhat limited to traditional designs and synthesis of various mesh materials, whereas meshes with multiple functions may be an effective approach to address long-standing challenges including postoperative complications. Herein, a bioresorbable electronic surgical mesh is presented that offers high mechanical strength over extended timeframes, wireless post-operative pressure monitoring, and on-demand drug delivery for the restoration of tissue structure and function. The study of materials and mesh layouts provides a wide range of tunability of mechanical and biochemical properties. Dissolvable dielectric composite with porous structure in a pyramidal shape enhances sensitivity of a wireless capacitive pressure sensor, and resistive microheaters integrated with inductive coils provide thermo-responsive drug delivery system for an antibacterial agent. In vivo evaluations demonstrate reliable, long-lived operation, and effective treatment for abdominal hernia defects, by clear evidence of suppressed complications such as adhesion formation and infections. A bioresorbable electronic surgical mesh is presented that offers high mechanical strength over extended timeframes, wireless post-operative pressure monitoring, and on-demand drug delivery for the restoration of tissue structure and function. In vivo evaluations demonstrate reliable, long-lived operation, and effective treatment for abdominal hernia defects, by clear evidence of suppressed complications such as adhesion formation and infections.image English WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim Soft, Long-Lived, Bioresorbable Electronic Surgical Mesh with Wireless Pressure Monitor and On-Demand Drug Delivery Article 10.1002/adma.202307391 1 Advanced Materials, v.36, no.11 Advanced Materials 36 11 N scie scopus 001123255600001 2-s2.0-85179322981 Chemistry, Multidisciplinary Chemistry, Physical Nanoscience & Nanotechnology Materials Science, Multidisciplinary Physics, Applied Physics, Condensed Matter Chemistry Science & Technology - Other Topics Materials Science Physics Article EPSILON-CAPROLACTONE NANOFIBERS HERNIA-REPAIR POLYPROPYLENE MESH INTRAABDOMINAL PRESSURE TRANSIENT REINFORCEMENT DEVICES BIOMATERIALS DEGRADATION DESIGN biodegradable elastomer hernia repair surgical mesh transient electronics wireless pressure sensor